Tolerability and acceptability of Blephagel: a novel eyelid hygiene aqueous gel

Serge DoanDepartment of Ophthalmology, Bichat Hospital and Foundation, Paris, FranceAbstract: Commonly associated with dry eye, blepharitis is the most commonly encountered disorder in general ophthalmologic practice. Although anti-infective and anti-inflammatory therapies are available, eyelid hygi...

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Autor principal:	Doan S
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/9a935f9601bc4d67a3abc41d970544c8
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spelling	oai:doaj.org-article:9a935f9601bc4d67a3abc41d970544c82021-12-02T08:44:10ZTolerability and acceptability of Blephagel: a novel eyelid hygiene aqueous gel1177-54671177-5483https://doaj.org/article/9a935f9601bc4d67a3abc41d970544c82012-01-01T00:00:00Zhttp://www.dovepress.com/tolerability-and-acceptability-of-blephagel-a-novel-eyelid-hygiene-aqu-a9037https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Serge DoanDepartment of Ophthalmology, Bichat Hospital and Foundation, Paris, FranceAbstract: Commonly associated with dry eye, blepharitis is the most commonly encountered disorder in general ophthalmologic practice. Although anti-infective and anti-inflammatory therapies are available, eyelid hygiene is the cornerstone of effective management. A variety of products have been used to assist and encourage eyelid cleansing and massage. The present study examines the ocular and periocular tolerability and acceptability of Blephagel, a cosmetic, poloxamer-containing gel designed specifically for cleansing the eyelid in subjects with sensitive skin or eyes or contact lens users. Subjects with blepharitis and sensitive skin or eyes, a history of atopy, or who use contact lenses applied Blephagel twice daily at home. Clinical ophthalmologic examinations were conducted before and 21 days after aqueous gel application, and subjects completed a questionnaire on the acceptability of the preparation. Thirty-three predominantly female subjects entered and completed the study. A total of 36% of the subjects had used similar products in the past, 21% regularly. Upon questioning by the ophthalmologist, 85% of the subjects reported acceptability of the preparation as good to very good, and 73% rated the efficacy as good to very good. There were minor but statistically nonsignificant changes in fluorescein tear breakup time and visual acuity before and after 21 days of aqueous gel application. The questionnaire results indicated that the subjects found the product to be effective for cleansing the eyelids of mucus and squama around eyelash roots. Moreover, cosmetic qualities, sensation in use, and acceptability were also appreciated. No subject reported any adverse event considered to be related to the aqueous gel. Although the safety of Blephagel has already been established in standard tests, the current results suggest that it is also pleasant to use and acceptable to blepharitis patients with sensitive skin as an aid to an eyelid hygiene regime.Keywords: blepharitis, tolerability, eyelid hygieneDoan SDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 71-77 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Doan S Tolerability and acceptability of Blephagel: a novel eyelid hygiene aqueous gel
description	Serge DoanDepartment of Ophthalmology, Bichat Hospital and Foundation, Paris, FranceAbstract: Commonly associated with dry eye, blepharitis is the most commonly encountered disorder in general ophthalmologic practice. Although anti-infective and anti-inflammatory therapies are available, eyelid hygiene is the cornerstone of effective management. A variety of products have been used to assist and encourage eyelid cleansing and massage. The present study examines the ocular and periocular tolerability and acceptability of Blephagel, a cosmetic, poloxamer-containing gel designed specifically for cleansing the eyelid in subjects with sensitive skin or eyes or contact lens users. Subjects with blepharitis and sensitive skin or eyes, a history of atopy, or who use contact lenses applied Blephagel twice daily at home. Clinical ophthalmologic examinations were conducted before and 21 days after aqueous gel application, and subjects completed a questionnaire on the acceptability of the preparation. Thirty-three predominantly female subjects entered and completed the study. A total of 36% of the subjects had used similar products in the past, 21% regularly. Upon questioning by the ophthalmologist, 85% of the subjects reported acceptability of the preparation as good to very good, and 73% rated the efficacy as good to very good. There were minor but statistically nonsignificant changes in fluorescein tear breakup time and visual acuity before and after 21 days of aqueous gel application. The questionnaire results indicated that the subjects found the product to be effective for cleansing the eyelids of mucus and squama around eyelash roots. Moreover, cosmetic qualities, sensation in use, and acceptability were also appreciated. No subject reported any adverse event considered to be related to the aqueous gel. Although the safety of Blephagel has already been established in standard tests, the current results suggest that it is also pleasant to use and acceptable to blepharitis patients with sensitive skin as an aid to an eyelid hygiene regime.Keywords: blepharitis, tolerability, eyelid hygiene
format	article
author	Doan S
author_facet	Doan S
author_sort	Doan S
title	Tolerability and acceptability of Blephagel: a novel eyelid hygiene aqueous gel
title_short	Tolerability and acceptability of Blephagel: a novel eyelid hygiene aqueous gel
title_full	Tolerability and acceptability of Blephagel: a novel eyelid hygiene aqueous gel
title_fullStr	Tolerability and acceptability of Blephagel: a novel eyelid hygiene aqueous gel
title_full_unstemmed	Tolerability and acceptability of Blephagel: a novel eyelid hygiene aqueous gel
title_sort	tolerability and acceptability of blephagel: a novel eyelid hygiene aqueous gel
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/9a935f9601bc4d67a3abc41d970544c8
work_keys_str_mv	AT doans tolerabilityandacceptabilityofblephagelanoveleyelidhygieneaqueousgel
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Tolerability and acceptability of Blephagel: a novel eyelid hygiene aqueous gel

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