FHOD1, a formin upregulated in epithelial-mesenchymal transition, participates in cancer cell migration and invasion.
Cancer cells can obtain their ability to invade and metastasise by undergoing epithelial-to-mesenchymal transition (EMT). Exploiting this mechanism of cellular plasticity, malignant cells can remodel their actin cytoskeleton and down-regulate proteins needed for cell-cell contacts. The mechanisms of...
Guardado en:
Autores principales: | Maria Gardberg, Katja Kaipio, Laura Lehtinen, Piia Mikkonen, Vanina D Heuser, Kati Talvinen, Kristiina Iljin, Caroline Kampf, Mathias Uhlen, Reidar Grénman, Mari Koivisto, Olli Carpén |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/9a9e4393398648228343bb90688dd4d8 |
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