High-throughput screen reveals sRNAs regulating crRNA biogenesis by targeting CRISPR leader to repress Rho termination
Small non-coding RNAs (sRNA) regulate bacterial functions by finding nucleic acids and proteins. Here the authors identify PhrS sRNA in Pseudomonas as a positive regulator of CRISPR, and show PhrS acts by binding to CRISPR leader, thereby preventing Rho-mediated transcription termination and promoti...
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Autores principales: | Ping Lin, Qinqin Pu, Qun Wu, Chuanmin Zhou, Biao Wang, Jacob Schettler, Zhihan Wang, Shugang Qin, Pan Gao, Rongpeng Li, Guoping Li, Zhenyu Cheng, Lefu Lan, Jianxin Jiang, Min Wu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/9aabe318c6e346aebdf2408f9a2e06b6 |
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