SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns

The length distribution of human pre-mRNA introns is very extensive. The authors demonstrate that splicing in a subset of short introns is dependent on SPF45 (RBM17), which replaces authentic U2AF-heterodimer on the truncated poly-pyrimidine tracts and interacts with the U2 snRNP protein SF3b155.

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Autores principales:	Kazuhiro Fukumura, Rei Yoshimoto, Luca Sperotto, Hyun-Seo Kang, Tetsuro Hirose, Kunio Inoue, Michael Sattler, Akila Mayeda
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9ab44e7770a74812b0cfe956d0384151
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spelling	oai:doaj.org-article:9ab44e7770a74812b0cfe956d03841512021-12-02T16:43:43ZSPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns10.1038/s41467-021-24879-y2041-1723https://doaj.org/article/9ab44e7770a74812b0cfe956d03841512021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24879-yhttps://doaj.org/toc/2041-1723The length distribution of human pre-mRNA introns is very extensive. The authors demonstrate that splicing in a subset of short introns is dependent on SPF45 (RBM17), which replaces authentic U2AF-heterodimer on the truncated poly-pyrimidine tracts and interacts with the U2 snRNP protein SF3b155.Kazuhiro FukumuraRei YoshimotoLuca SperottoHyun-Seo KangTetsuro HiroseKunio InoueMichael SattlerAkila MayedaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kazuhiro Fukumura Rei Yoshimoto Luca Sperotto Hyun-Seo Kang Tetsuro Hirose Kunio Inoue Michael Sattler Akila Mayeda SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns
description	The length distribution of human pre-mRNA introns is very extensive. The authors demonstrate that splicing in a subset of short introns is dependent on SPF45 (RBM17), which replaces authentic U2AF-heterodimer on the truncated poly-pyrimidine tracts and interacts with the U2 snRNP protein SF3b155.
format	article
author	Kazuhiro Fukumura Rei Yoshimoto Luca Sperotto Hyun-Seo Kang Tetsuro Hirose Kunio Inoue Michael Sattler Akila Mayeda
author_facet	Kazuhiro Fukumura Rei Yoshimoto Luca Sperotto Hyun-Seo Kang Tetsuro Hirose Kunio Inoue Michael Sattler Akila Mayeda
author_sort	Kazuhiro Fukumura
title	SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns
title_short	SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns
title_full	SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns
title_fullStr	SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns
title_full_unstemmed	SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns
title_sort	spf45/rbm17-dependent, but not u2af-dependent, splicing in a distinct subset of human short introns
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9ab44e7770a74812b0cfe956d0384151
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SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns

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