Time-invariant working memory representations in the presence of code-morphing in the lateral prefrontal cortex

Working memory is maintained in the recurrent connectivity of prefrontal neurons; however, distractors lead to a morphing of the population code. Here, the authors show that a low dimensional subspace of activity maintains memory information even with a distractor and can be modeled as a bump attrac...

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Autores principales: Aishwarya Parthasarathy, Cheng Tang, Roger Herikstad, Loong Fah Cheong, Shih-Cheng Yen, Camilo Libedinsky
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9abc5a7692b34c9ba6468363ce268ddf
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spelling oai:doaj.org-article:9abc5a7692b34c9ba6468363ce268ddf2021-12-02T16:57:22ZTime-invariant working memory representations in the presence of code-morphing in the lateral prefrontal cortex10.1038/s41467-019-12841-y2041-1723https://doaj.org/article/9abc5a7692b34c9ba6468363ce268ddf2019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12841-yhttps://doaj.org/toc/2041-1723Working memory is maintained in the recurrent connectivity of prefrontal neurons; however, distractors lead to a morphing of the population code. Here, the authors show that a low dimensional subspace of activity maintains memory information even with a distractor and can be modeled as a bump attractor.Aishwarya ParthasarathyCheng TangRoger HerikstadLoong Fah CheongShih-Cheng YenCamilo LibedinskyNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aishwarya Parthasarathy
Cheng Tang
Roger Herikstad
Loong Fah Cheong
Shih-Cheng Yen
Camilo Libedinsky
Time-invariant working memory representations in the presence of code-morphing in the lateral prefrontal cortex
description Working memory is maintained in the recurrent connectivity of prefrontal neurons; however, distractors lead to a morphing of the population code. Here, the authors show that a low dimensional subspace of activity maintains memory information even with a distractor and can be modeled as a bump attractor.
format article
author Aishwarya Parthasarathy
Cheng Tang
Roger Herikstad
Loong Fah Cheong
Shih-Cheng Yen
Camilo Libedinsky
author_facet Aishwarya Parthasarathy
Cheng Tang
Roger Herikstad
Loong Fah Cheong
Shih-Cheng Yen
Camilo Libedinsky
author_sort Aishwarya Parthasarathy
title Time-invariant working memory representations in the presence of code-morphing in the lateral prefrontal cortex
title_short Time-invariant working memory representations in the presence of code-morphing in the lateral prefrontal cortex
title_full Time-invariant working memory representations in the presence of code-morphing in the lateral prefrontal cortex
title_fullStr Time-invariant working memory representations in the presence of code-morphing in the lateral prefrontal cortex
title_full_unstemmed Time-invariant working memory representations in the presence of code-morphing in the lateral prefrontal cortex
title_sort time-invariant working memory representations in the presence of code-morphing in the lateral prefrontal cortex
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/9abc5a7692b34c9ba6468363ce268ddf
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