CRISPR-Cas-Mediated Gene Silencing Reveals RacR To Be a Negative Regulator of YdaS and YdaT Toxins in <named-content content-type="genus-species">Escherichia coli</named-content> K-12

ABSTRACT Bacterial genomes are rich in horizontally acquired prophages. racR is an essential gene located in the rac prophage that is resident in many Escherichia coli genomes. Employing a clustered regularly interspaced short palindromic repeat (CRISPR)-Cas-based gene silencing approach, we show th...

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Bibliographic Details
Main Authors: Gargi Bindal, Revathy Krishnamurthi, Aswin Sai Narain Seshasayee, Devashish Rath
Format: article
Language:EN
Published: American Society for Microbiology 2017
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Online Access:https://doaj.org/article/9abd19a9973749ea81d18f7943e7fada
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