Direct binding of TFEα opens DNA binding cleft of RNA polymerase
How clamp conformation is regulated in the transcription cycle of stalk-containing archaeal and eukaryotic RNA polymerase (RNAP) systems is still not well understood. Here, the authors combine cryo-EM, X-ray crystallography and photo-crosslinking assays to structurally characterise RNAP, the RNAP-TF...
Guardado en:
Autores principales: | Sung-Hoon Jun, Jaekyung Hyun, Jeong Seok Cha, Hoyoung Kim, Michael S. Bartlett, Hyun-Soo Cho, Katsuhiko S. Murakami |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9ace4ca1aed44741b400bd87ec0e18c7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Translation Inhibitors Activate Autophagy Master Regulators TFEB and TFE3
por: Thao Thi Dang, et al.
Publicado: (2021) -
Crystal structure and functional characterization of a light-driven chloride pump having an NTQ motif
por: Kuglae Kim, et al.
Publicado: (2016) -
Remarkable hexafunctional anion receptor with operational urea-based inner cleft and thiourea-based outer cleft: Novel design with high-efficiency for sulfate binding
por: Maryam Emami Khansari, et al.
Publicado: (2017) -
Point of care airway ultrasound to select tracheal tube and determine insertion depth in cleft repair surgery
por: Jung Hwan Ahn, et al.
Publicado: (2021) -
Tessier number 7 cleft with unilateral complete cleft lip and palate: a case report
por: Hyun Seung Lee, et al.
Publicado: (2021)