HIV-1 Nef-induced cardiotoxicity through dysregulation of autophagy

Abstract Cardiovascular disease is a leading cause of co-morbidity in HIV-1 positive patients, even those in whom plasma virus levels are well-controlled. The pathogenic mechanism of HIV-1-associated cardiomyopathy is unknown, but has been presumed to be mediated indirectly, owing to the absence of...

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Autores principales: Manish K. Gupta, Rafal Kaminski, Brian Mullen, Jennifer Gordon, Tricia H. Burdo, Joseph Y. Cheung, Arthur M. Feldman, Muniswamy Madesh, Kamel Khalili
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/9ad17bb03abc452586a3880c4d4e1833
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