An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways

The CD8 T cell response to Zika virus is known to be a critical component of the host immune response to infection. Here the authors show a Zika virus isolate specific disruption of antigen processing that impacts the host response and impairs viral clearance providing evidence of isolate specific i...

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Autores principales:	Ryan D. Pardy, Stefanie F. Valbon, Brendan Cordeiro, Connie M. Krawczyk, Martin J. Richer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9ad3084949b04a9a9eb30dc2b3b1576b
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spelling	oai:doaj.org-article:9ad3084949b04a9a9eb30dc2b3b1576b2021-12-02T14:34:12ZAn epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways10.1038/s41467-021-24340-02041-1723https://doaj.org/article/9ad3084949b04a9a9eb30dc2b3b1576b2021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24340-0https://doaj.org/toc/2041-1723The CD8 T cell response to Zika virus is known to be a critical component of the host immune response to infection. Here the authors show a Zika virus isolate specific disruption of antigen processing that impacts the host response and impairs viral clearance providing evidence of isolate specific impacts on the immune response to infectionRyan D. PardyStefanie F. ValbonBrendan CordeiroConnie M. KrawczykMartin J. RicherNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ryan D. Pardy Stefanie F. Valbon Brendan Cordeiro Connie M. Krawczyk Martin J. Richer An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways
description	The CD8 T cell response to Zika virus is known to be a critical component of the host immune response to infection. Here the authors show a Zika virus isolate specific disruption of antigen processing that impacts the host response and impairs viral clearance providing evidence of isolate specific impacts on the immune response to infection
format	article
author	Ryan D. Pardy Stefanie F. Valbon Brendan Cordeiro Connie M. Krawczyk Martin J. Richer
author_facet	Ryan D. Pardy Stefanie F. Valbon Brendan Cordeiro Connie M. Krawczyk Martin J. Richer
author_sort	Ryan D. Pardy
title	An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways
title_short	An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways
title_full	An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways
title_fullStr	An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways
title_full_unstemmed	An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways
title_sort	epidemic zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9ad3084949b04a9a9eb30dc2b3b1576b
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An epidemic Zika virus isolate suppresses antiviral immunity by disrupting antigen presentation pathways

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