A multi-task convolutional deep neural network for variant calling in single molecule sequencing

A multi-task convolutional deep neural network for variant calling in single molecule sequencing

Single Molecule Sequencing (SMS) technologies generate long but noisy reads data. Here, the authors develop Clairvoyante, a deep neural network-based method for variant calling with SMS reads such as PacBio and ONT data.

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Detalles Bibliográficos
Autores principales: Ruibang Luo, Fritz J. Sedlazeck, Tak-Wah Lam, Michael C. Schatz
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/9ad545dd5e814a6f9351c9241b1c6be7
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