Genome-wide profiling of adenine base editor specificity by EndoV-seq

Adenine base editors are an important contribution to the genome editing toolbox. Here the authors present EndoV-seq, an endonuclease-based assay for evaluating genomewide off-target effects of base editing.

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Autores principales:	Puping Liang, Xiaowei Xie, Shengyao Zhi, Hongwei Sun, Xiya Zhang, Yu Chen, Yuxi Chen, Yuanyan Xiong, Wenbin Ma, Dan Liu, Junjiu Huang, Zhou Songyang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9adb579e346e4808b53fd91405b7605e
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spelling	oai:doaj.org-article:9adb579e346e4808b53fd91405b7605e2021-12-02T17:31:21ZGenome-wide profiling of adenine base editor specificity by EndoV-seq10.1038/s41467-018-07988-z2041-1723https://doaj.org/article/9adb579e346e4808b53fd91405b7605e2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07988-zhttps://doaj.org/toc/2041-1723Adenine base editors are an important contribution to the genome editing toolbox. Here the authors present EndoV-seq, an endonuclease-based assay for evaluating genomewide off-target effects of base editing.Puping LiangXiaowei XieShengyao ZhiHongwei SunXiya ZhangYu ChenYuxi ChenYuanyan XiongWenbin MaDan LiuJunjiu HuangZhou SongyangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Puping Liang Xiaowei Xie Shengyao Zhi Hongwei Sun Xiya Zhang Yu Chen Yuxi Chen Yuanyan Xiong Wenbin Ma Dan Liu Junjiu Huang Zhou Songyang Genome-wide profiling of adenine base editor specificity by EndoV-seq
description	Adenine base editors are an important contribution to the genome editing toolbox. Here the authors present EndoV-seq, an endonuclease-based assay for evaluating genomewide off-target effects of base editing.
format	article
author	Puping Liang Xiaowei Xie Shengyao Zhi Hongwei Sun Xiya Zhang Yu Chen Yuxi Chen Yuanyan Xiong Wenbin Ma Dan Liu Junjiu Huang Zhou Songyang
author_facet	Puping Liang Xiaowei Xie Shengyao Zhi Hongwei Sun Xiya Zhang Yu Chen Yuxi Chen Yuanyan Xiong Wenbin Ma Dan Liu Junjiu Huang Zhou Songyang
author_sort	Puping Liang
title	Genome-wide profiling of adenine base editor specificity by EndoV-seq
title_short	Genome-wide profiling of adenine base editor specificity by EndoV-seq
title_full	Genome-wide profiling of adenine base editor specificity by EndoV-seq
title_fullStr	Genome-wide profiling of adenine base editor specificity by EndoV-seq
title_full_unstemmed	Genome-wide profiling of adenine base editor specificity by EndoV-seq
title_sort	genome-wide profiling of adenine base editor specificity by endov-seq
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/9adb579e346e4808b53fd91405b7605e
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Genome-wide profiling of adenine base editor specificity by EndoV-seq

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