Genome-wide profiling of adenine base editor specificity by EndoV-seq

Genome-wide profiling of adenine base editor specificity by EndoV-seq

Adenine base editors are an important contribution to the genome editing toolbox. Here the authors present EndoV-seq, an endonuclease-based assay for evaluating genomewide off-target effects of base editing.

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Detalles Bibliográficos
Autores principales: Puping Liang, Xiaowei Xie, Shengyao Zhi, Hongwei Sun, Xiya Zhang, Yu Chen, Yuxi Chen, Yuanyan Xiong, Wenbin Ma, Dan Liu, Junjiu Huang, Zhou Songyang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
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Acceso en línea:https://doaj.org/article/9adb579e346e4808b53fd91405b7605e
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