Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity

How the immune responses induced by SARS-CoV-2 and human coronavirus (hCoV) crosstalk is still unclear. Here the authors profile the humoral responses of prepandemic and SARS-CoV-2-infected donors to find that higher hCoV antibody titers are associated with SARS-CoV-2 negativity, and with reduced ho...

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Autores principales:	Irene A. Abela, Chloé Pasin, Magdalena Schwarzmüller, Selina Epp, Michèle E. Sickmann, Merle M. Schanz, Peter Rusert, Jacqueline Weber, Stefan Schmutz, Annette Audigé, Liridona Maliqi, Annika Hunziker, Maria C. Hesselman, Cyrille R. Niklaus, Jochen Gottschalk, Eméry Schindler, Alexander Wepf, Urs Karrer, Aline Wolfensberger, Silvana K. Rampini, Patrick M. Meyer Sauteur, Christoph Berger, Michael Huber, Jürg Böni, Dominique L. Braun, Maddalena Marconato, Markus G. Manz, Beat M. Frey, Huldrych F. Günthard, Roger D. Kouyos, Alexandra Trkola
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9ae1432b592c419493eac058f90406ee
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spelling	oai:doaj.org-article:9ae1432b592c419493eac058f90406ee2021-11-21T12:34:04ZMultifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity10.1038/s41467-021-27040-x2041-1723https://doaj.org/article/9ae1432b592c419493eac058f90406ee2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27040-xhttps://doaj.org/toc/2041-1723How the immune responses induced by SARS-CoV-2 and human coronavirus (hCoV) crosstalk is still unclear. Here the authors profile the humoral responses of prepandemic and SARS-CoV-2-infected donors to find that higher hCoV antibody titers are associated with SARS-CoV-2 negativity, and with reduced hospitalization in SARS-CoV-2 positive patients.Irene A. AbelaChloé PasinMagdalena SchwarzmüllerSelina EppMichèle E. SickmannMerle M. SchanzPeter RusertJacqueline WeberStefan SchmutzAnnette AudigéLiridona MaliqiAnnika HunzikerMaria C. HesselmanCyrille R. NiklausJochen GottschalkEméry SchindlerAlexander WepfUrs KarrerAline WolfensbergerSilvana K. RampiniPatrick M. Meyer SauteurChristoph BergerMichael HuberJürg BöniDominique L. BraunMaddalena MarconatoMarkus G. ManzBeat M. FreyHuldrych F. GünthardRoger D. KouyosAlexandra TrkolaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Irene A. Abela Chloé Pasin Magdalena Schwarzmüller Selina Epp Michèle E. Sickmann Merle M. Schanz Peter Rusert Jacqueline Weber Stefan Schmutz Annette Audigé Liridona Maliqi Annika Hunziker Maria C. Hesselman Cyrille R. Niklaus Jochen Gottschalk Eméry Schindler Alexander Wepf Urs Karrer Aline Wolfensberger Silvana K. Rampini Patrick M. Meyer Sauteur Christoph Berger Michael Huber Jürg Böni Dominique L. Braun Maddalena Marconato Markus G. Manz Beat M. Frey Huldrych F. Günthard Roger D. Kouyos Alexandra Trkola Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity
description	How the immune responses induced by SARS-CoV-2 and human coronavirus (hCoV) crosstalk is still unclear. Here the authors profile the humoral responses of prepandemic and SARS-CoV-2-infected donors to find that higher hCoV antibody titers are associated with SARS-CoV-2 negativity, and with reduced hospitalization in SARS-CoV-2 positive patients.
format	article
author	Irene A. Abela Chloé Pasin Magdalena Schwarzmüller Selina Epp Michèle E. Sickmann Merle M. Schanz Peter Rusert Jacqueline Weber Stefan Schmutz Annette Audigé Liridona Maliqi Annika Hunziker Maria C. Hesselman Cyrille R. Niklaus Jochen Gottschalk Eméry Schindler Alexander Wepf Urs Karrer Aline Wolfensberger Silvana K. Rampini Patrick M. Meyer Sauteur Christoph Berger Michael Huber Jürg Böni Dominique L. Braun Maddalena Marconato Markus G. Manz Beat M. Frey Huldrych F. Günthard Roger D. Kouyos Alexandra Trkola
author_facet	Irene A. Abela Chloé Pasin Magdalena Schwarzmüller Selina Epp Michèle E. Sickmann Merle M. Schanz Peter Rusert Jacqueline Weber Stefan Schmutz Annette Audigé Liridona Maliqi Annika Hunziker Maria C. Hesselman Cyrille R. Niklaus Jochen Gottschalk Eméry Schindler Alexander Wepf Urs Karrer Aline Wolfensberger Silvana K. Rampini Patrick M. Meyer Sauteur Christoph Berger Michael Huber Jürg Böni Dominique L. Braun Maddalena Marconato Markus G. Manz Beat M. Frey Huldrych F. Günthard Roger D. Kouyos Alexandra Trkola
author_sort	Irene A. Abela
title	Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity
title_short	Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity
title_full	Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity
title_fullStr	Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity
title_full_unstemmed	Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity
title_sort	multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to sars-cov-2 immunity
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9ae1432b592c419493eac058f90406ee
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Multifactorial seroprofiling dissects the contribution of pre-existing human coronaviruses responses to SARS-CoV-2 immunity

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