Inorganic nanolayers: structure, preparation, and biomedical applications

Bullo Saifullah, Mohd Zobir B HusseinMaterials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, Serdang, MalaysiaAbstract: Hydrotalcite-like compounds are two-dimensional inorganic nanolayers also known as clay minerals or anionic clays o...

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Autores principales: Saifullah B, Hussein MZB
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Publicado: Dove Medical Press 2015
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spelling oai:doaj.org-article:9af0bf5f140a467fb4cd8b9dda8471652021-12-02T04:33:04ZInorganic nanolayers: structure, preparation, and biomedical applications1178-2013https://doaj.org/article/9af0bf5f140a467fb4cd8b9dda8471652015-09-01T00:00:00Zhttp://www.dovepress.com/inorganic-nanolayers-structure-preparation-andnbspbiomedical-applicati-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Bullo Saifullah, Mohd Zobir B HusseinMaterials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, Serdang, MalaysiaAbstract: Hydrotalcite-like compounds are two-dimensional inorganic nanolayers also known as clay minerals or anionic clays or layered double hydroxides/layered hydroxy salts, and have emerged as a single type of material with numerous biomedical applications, such as drug delivery, gene delivery, cosmetics, and biosensing. Inorganic nanolayers are promising materials due to their fascinating properties, such as ease of preparation, ability to intercalate different type of anions (inorganic, organic, biomolecules, and even genes), high thermal stability, delivery of intercalated anions in a sustained manner, high biocompatibility, and easy biodegradation. Inorganic nanolayers have been the focus for researchers over the last decade, resulting in widening application horizons, especially in the field of biomedical science. These nanolayers have been widely applied in drug and gene delivery. They have also been applied in biosensing technology, and most recently in bioimaging science. The suitability of inorganic nanolayers for application in drug delivery, gene delivery, biosensing technology, and bioimaging science makes them ideal materials to be applied for theranostic purposes. In this paper, we review the structure, methods of preparation, and latest advances made by inorganic nanolayers in such biomedical applications as drug delivery, gene delivery, biosensing, and bioimaging.Keywords: inorganic nanolayers, layered double hydroxides, layered hydroxy salts, drug delivery, biosensors, bioimagingSaifullah BHussein MZBDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2015, Iss default, Pp 5609-5633 (2015)
institution DOAJ
collection DOAJ
language EN
topic Medicine (General)
R5-920
spellingShingle Medicine (General)
R5-920
Saifullah B
Hussein MZB
Inorganic nanolayers: structure, preparation, and biomedical applications
description Bullo Saifullah, Mohd Zobir B HusseinMaterials Synthesis and Characterization Laboratory, Institute of Advanced Technology (ITMA), Universiti Putra Malaysia, Serdang, MalaysiaAbstract: Hydrotalcite-like compounds are two-dimensional inorganic nanolayers also known as clay minerals or anionic clays or layered double hydroxides/layered hydroxy salts, and have emerged as a single type of material with numerous biomedical applications, such as drug delivery, gene delivery, cosmetics, and biosensing. Inorganic nanolayers are promising materials due to their fascinating properties, such as ease of preparation, ability to intercalate different type of anions (inorganic, organic, biomolecules, and even genes), high thermal stability, delivery of intercalated anions in a sustained manner, high biocompatibility, and easy biodegradation. Inorganic nanolayers have been the focus for researchers over the last decade, resulting in widening application horizons, especially in the field of biomedical science. These nanolayers have been widely applied in drug and gene delivery. They have also been applied in biosensing technology, and most recently in bioimaging science. The suitability of inorganic nanolayers for application in drug delivery, gene delivery, biosensing technology, and bioimaging science makes them ideal materials to be applied for theranostic purposes. In this paper, we review the structure, methods of preparation, and latest advances made by inorganic nanolayers in such biomedical applications as drug delivery, gene delivery, biosensing, and bioimaging.Keywords: inorganic nanolayers, layered double hydroxides, layered hydroxy salts, drug delivery, biosensors, bioimaging
format article
author Saifullah B
Hussein MZB
author_facet Saifullah B
Hussein MZB
author_sort Saifullah B
title Inorganic nanolayers: structure, preparation, and biomedical applications
title_short Inorganic nanolayers: structure, preparation, and biomedical applications
title_full Inorganic nanolayers: structure, preparation, and biomedical applications
title_fullStr Inorganic nanolayers: structure, preparation, and biomedical applications
title_full_unstemmed Inorganic nanolayers: structure, preparation, and biomedical applications
title_sort inorganic nanolayers: structure, preparation, and biomedical applications
publisher Dove Medical Press
publishDate 2015
url https://doaj.org/article/9af0bf5f140a467fb4cd8b9dda847165
work_keys_str_mv AT saifullahb inorganicnanolayersstructurepreparationandnbspbiomedicalapplications
AT husseinmzb inorganicnanolayersstructurepreparationandnbspbiomedicalapplications
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