Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft)

Feyzahan Ekici, Marlene R Moster, Victor Cvintal, Wanda D Hu, Michael Waisbourd Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA, USA Purpose: To investigate the clinical outcomes of tube shunt coverage using sterile gamma-irradiated cornea allograft.Patients and methods: The Wills E...

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Autores principales:	Ekici F, Moster MR, Cvintal V, Hu WD, Waisbourd M
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/9b02e94200bf4ec8bfbc6273c9f2a88e
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spelling	oai:doaj.org-article:9b02e94200bf4ec8bfbc6273c9f2a88e2021-12-02T06:26:04ZTube shunt coverage with gamma-irradiated cornea allograft (VisionGraft)1177-5483https://doaj.org/article/9b02e94200bf4ec8bfbc6273c9f2a88e2015-04-01T00:00:00Zhttp://www.dovepress.com/tube-shunt-coverage-with-gamma-irradiated-cornea-allograft-visiongraft-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Feyzahan Ekici, Marlene R Moster, Victor Cvintal, Wanda D Hu, Michael Waisbourd Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA, USA Purpose: To investigate the clinical outcomes of tube shunt coverage using sterile gamma-irradiated cornea allograft.Patients and methods: The Wills Eye Hospital Glaucoma Research Center retrospectively reviewed the medical records of 165 patients who underwent glaucoma tube shunt procedures using sterile gamma-irradiated cornea allograft (VisionGraft) between December 2012 and November 2013. Demographic characteristics, type of tube shunt, and position were noted. Complications were recorded at 1 day; 1 week; 1, 3, 6, and 12 months; and on the final postoperative visit.Results: One hundred and sixty-nine eyes of 165 patients were included. The mean follow-up time was 4.8±3.5 (ranging from 1 to 16) months. There was no evidence of immunological reaction, infection, or exposure in 166 eyes (98.2%). Three eyes (1.8%) experienced graft or tube exposure within the first 3 postoperative months. Two of the cases had underlying diseases: bullous pemphigoid and chronic allergic conjunctivitis.Conclusion: Coverage of tube shunts using gamma-irradiated cornea allograft had a low exposure rate and was well tolerated. The graft can be stored long term at room temperature and has an excellent postoperative cosmetic appearance.Keywords: aqueous shunts, gamma-irradiated cornea allograft, glaucoma drainage device, tube shunt surgery Ekici FMoster MRCvintal VHu WDWaisbourd MDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2015, Iss default, Pp 751-755 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Ekici F Moster MR Cvintal V Hu WD Waisbourd M Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft)
description	Feyzahan Ekici, Marlene R Moster, Victor Cvintal, Wanda D Hu, Michael Waisbourd Glaucoma Research Center, Wills Eye Hospital, Philadelphia, PA, USA Purpose: To investigate the clinical outcomes of tube shunt coverage using sterile gamma-irradiated cornea allograft.Patients and methods: The Wills Eye Hospital Glaucoma Research Center retrospectively reviewed the medical records of 165 patients who underwent glaucoma tube shunt procedures using sterile gamma-irradiated cornea allograft (VisionGraft) between December 2012 and November 2013. Demographic characteristics, type of tube shunt, and position were noted. Complications were recorded at 1 day; 1 week; 1, 3, 6, and 12 months; and on the final postoperative visit.Results: One hundred and sixty-nine eyes of 165 patients were included. The mean follow-up time was 4.8±3.5 (ranging from 1 to 16) months. There was no evidence of immunological reaction, infection, or exposure in 166 eyes (98.2%). Three eyes (1.8%) experienced graft or tube exposure within the first 3 postoperative months. Two of the cases had underlying diseases: bullous pemphigoid and chronic allergic conjunctivitis.Conclusion: Coverage of tube shunts using gamma-irradiated cornea allograft had a low exposure rate and was well tolerated. The graft can be stored long term at room temperature and has an excellent postoperative cosmetic appearance.Keywords: aqueous shunts, gamma-irradiated cornea allograft, glaucoma drainage device, tube shunt surgery
format	article
author	Ekici F Moster MR Cvintal V Hu WD Waisbourd M
author_facet	Ekici F Moster MR Cvintal V Hu WD Waisbourd M
author_sort	Ekici F
title	Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft)
title_short	Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft)
title_full	Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft)
title_fullStr	Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft)
title_full_unstemmed	Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft)
title_sort	tube shunt coverage with gamma-irradiated cornea allograft (visiongraft)
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/9b02e94200bf4ec8bfbc6273c9f2a88e
work_keys_str_mv	AT ekicif tubeshuntcoveragewithgammairradiatedcorneaallograftvisiongraft AT mostermr tubeshuntcoveragewithgammairradiatedcorneaallograftvisiongraft AT cvintalv tubeshuntcoveragewithgammairradiatedcorneaallograftvisiongraft AT huwd tubeshuntcoveragewithgammairradiatedcorneaallograftvisiongraft AT waisbourdm tubeshuntcoveragewithgammairradiatedcorneaallograftvisiongraft
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Tube shunt coverage with gamma-irradiated cornea allograft (VisionGraft)

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