Testicular somatic cell-like cells derived from embryonic stem cells induce differentiation of epiblasts into germ cells

Testicular somatic cell-like cells derived from embryonic stem cells induce differentiation of epiblasts into germ cells

Rore et al generate testicular somatic cell-like cells (TesLCs) including Sertoli cell-like cells from mouse embryonic stem cells in xeno-free culture. They created testicular organoids in aggregation co-culture of TesLCs and epiblast-like cells (EpiLCs) and also find that TesLC-conditioned media pr...

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Detalles Bibliográficos
Autores principales: Holly Rore, Nicholas Owen, Raul Eduardo Piña-Aguilar, Kevin Docherty, Ryohei Sekido
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/9b0d77b189cb48598785fe29b0ee4f1d
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