ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function.

ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function.

Oxidative stress in the central nervous system mediates the increase in sympathetic tone that precedes the development of hypertension. We hypothesized that by transforming Angiotensin-II (AngII) into Ang-(1-7), ACE2 might reduce AngII-mediated oxidative stress in the brain and prevent autonomic dys...

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Autores principales: Huijing Xia, Sonia Suda, Sharell Bindom, Yumei Feng, Susan B Gurley, Dale Seth, L Gabriel Navar, Eric Lazartigues
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/9b1bf537bb3d4e0b96a8ec1db06802fd
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