Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs

Caspase-1 cleaves PPARγ for potentiating the pro-tumor action of TAMs

Tumor associated macrophages (TAMs) promote cancer progression. Here, the author show that caspase-1 promotes TAMs differentiation by attenuating medium-chain acyl-CoA dehydrogenase activity and that inhibition of this axis results in suppression of tumour growth in a transgenic mouse model of breas...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zhiyuan Niu, Qian Shi, Wenlong Zhang, Yuxin Shu, Nanfei Yang, Bing Chen, Qingsong Wang, Xuyang Zhao, Jiajia Chen, Nan Cheng, Xiujing Feng, Zichun Hua, Jianguo Ji, Pingping Shen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/9b1dfe9c6f8041e2a2d8b1d09e428ffc
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares