Comparison of Plasma C- Reactive Protein Levels in Pseudoexfoliation (PXF) Glaucoma with Normal Population

BACKGROUND AND OBJECTIVE: Pseudoexfoliation (PXF) glaucoma is a senile disease which affects anterior segment structures of eyes. Pseudoexfoliation material has also been found in heart, lung, liver, gall bladder, cerebral meninges, skin, and blood vessels and is thought to be a systemic disorder. C...

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Autores principales:	R Zarei, M Nili Ahmadabadi, A Eftekharzadeh
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2010
Materias:	c- reactive protein pseudoexfoliation inflammation Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9b1e308b3a844234955ec47d732922c4
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spelling	oai:doaj.org-article:9b1e308b3a844234955ec47d732922c42021-11-10T09:00:30ZComparison of Plasma C- Reactive Protein Levels in Pseudoexfoliation (PXF) Glaucoma with Normal Population1561-41072251-7170https://doaj.org/article/9b1e308b3a844234955ec47d732922c42010-08-01T00:00:00Zhttp://jbums.org/article-1-3630-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Pseudoexfoliation (PXF) glaucoma is a senile disease which affects anterior segment structures of eyes. Pseudoexfoliation material has also been found in heart, lung, liver, gall bladder, cerebral meninges, skin, and blood vessels and is thought to be a systemic disorder. C- reactive protein (CRP) is an acute phase reactant found to be an important and sensitive marker of systemic inflammatory states and disorders. The purpose of this study was to determine the plasma C- reactive protein levels in pseudoexfoliation glaucoma and compare with normal population.METHODS: This case controlled study was performed on 73 cases that referred to Farabi eye hospital in Tehran. Patients were divided into two groups: 39 cases PXF glaucoma without any other ocular and systemic disorder and 34 controls, with no evidence of PXF glaucoma. In both groups, patients with blood pressure, CNS and cardiovascular diseases were excluded. Plasma CRP levels of all the study participants were determined and compared.FINDINGS: The mean age was 68.4±6.4 years in case group and was 65.3±7.2 years in control group. The mean plasma CRP level in patients was 1.85±2.52 and in normal people was 1.66±1.64. Plasma CPR levels were not different in the PXF cases with controls. There was no relationship between CRP level and the disease in male and female groups in different ages. CONCLUSION: Our findings suggest that PXF may not be associated with plasma CRP levels and inflammatory causes of PXF glaucoma is debate.R ZareiM Nili AhmadabadiA EftekharzadehBabol University of Medical Sciencesarticlec- reactive proteinpseudoexfoliationinflammationMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 12, Iss 3, Pp 38-42 (2010)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	c- reactive protein pseudoexfoliation inflammation Medicine R Medicine (General) R5-920
spellingShingle	c- reactive protein pseudoexfoliation inflammation Medicine R Medicine (General) R5-920 R Zarei M Nili Ahmadabadi A Eftekharzadeh Comparison of Plasma C- Reactive Protein Levels in Pseudoexfoliation (PXF) Glaucoma with Normal Population
description	BACKGROUND AND OBJECTIVE: Pseudoexfoliation (PXF) glaucoma is a senile disease which affects anterior segment structures of eyes. Pseudoexfoliation material has also been found in heart, lung, liver, gall bladder, cerebral meninges, skin, and blood vessels and is thought to be a systemic disorder. C- reactive protein (CRP) is an acute phase reactant found to be an important and sensitive marker of systemic inflammatory states and disorders. The purpose of this study was to determine the plasma C- reactive protein levels in pseudoexfoliation glaucoma and compare with normal population.METHODS: This case controlled study was performed on 73 cases that referred to Farabi eye hospital in Tehran. Patients were divided into two groups: 39 cases PXF glaucoma without any other ocular and systemic disorder and 34 controls, with no evidence of PXF glaucoma. In both groups, patients with blood pressure, CNS and cardiovascular diseases were excluded. Plasma CRP levels of all the study participants were determined and compared.FINDINGS: The mean age was 68.4±6.4 years in case group and was 65.3±7.2 years in control group. The mean plasma CRP level in patients was 1.85±2.52 and in normal people was 1.66±1.64. Plasma CPR levels were not different in the PXF cases with controls. There was no relationship between CRP level and the disease in male and female groups in different ages. CONCLUSION: Our findings suggest that PXF may not be associated with plasma CRP levels and inflammatory causes of PXF glaucoma is debate.
format	article
author	R Zarei M Nili Ahmadabadi A Eftekharzadeh
author_facet	R Zarei M Nili Ahmadabadi A Eftekharzadeh
author_sort	R Zarei
title	Comparison of Plasma C- Reactive Protein Levels in Pseudoexfoliation (PXF) Glaucoma with Normal Population
title_short	Comparison of Plasma C- Reactive Protein Levels in Pseudoexfoliation (PXF) Glaucoma with Normal Population
title_full	Comparison of Plasma C- Reactive Protein Levels in Pseudoexfoliation (PXF) Glaucoma with Normal Population
title_fullStr	Comparison of Plasma C- Reactive Protein Levels in Pseudoexfoliation (PXF) Glaucoma with Normal Population
title_full_unstemmed	Comparison of Plasma C- Reactive Protein Levels in Pseudoexfoliation (PXF) Glaucoma with Normal Population
title_sort	comparison of plasma c- reactive protein levels in pseudoexfoliation (pxf) glaucoma with normal population
publisher	Babol University of Medical Sciences
publishDate	2010
url	https://doaj.org/article/9b1e308b3a844234955ec47d732922c4
work_keys_str_mv	AT rzarei comparisonofplasmacreactiveproteinlevelsinpseudoexfoliationpxfglaucomawithnormalpopulation AT mniliahmadabadi comparisonofplasmacreactiveproteinlevelsinpseudoexfoliationpxfglaucomawithnormalpopulation AT aeftekharzadeh comparisonofplasmacreactiveproteinlevelsinpseudoexfoliationpxfglaucomawithnormalpopulation
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Comparison of Plasma C- Reactive Protein Levels in Pseudoexfoliation (PXF) Glaucoma with Normal Population

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