Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment

Oral microbiota delivery is an approach to treat and prevent disease but suffers from low retention and bioavailability. Here the authors report on a lipid coating to protect against environmental assault maintaining viability and bioactivity of the bacteria and demonstrate effective application in...

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Bibliographic Details
Main Authors: Zhenping Cao, Xinyue Wang, Yan Pang, Shanshan Cheng, Jinyao Liu
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/9b1f08e6b5b442da8defad2bf3d2782c
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Summary:Oral microbiota delivery is an approach to treat and prevent disease but suffers from low retention and bioavailability. Here the authors report on a lipid coating to protect against environmental assault maintaining viability and bioactivity of the bacteria and demonstrate effective application in a colitis model.