Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment

Oral microbiota delivery is an approach to treat and prevent disease but suffers from low retention and bioavailability. Here the authors report on a lipid coating to protect against environmental assault maintaining viability and bioactivity of the bacteria and demonstrate effective application in...

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Autores principales: Zhenping Cao, Xinyue Wang, Yan Pang, Shanshan Cheng, Jinyao Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9b1f08e6b5b442da8defad2bf3d2782c
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spelling oai:doaj.org-article:9b1f08e6b5b442da8defad2bf3d2782c2021-12-02T13:27:23ZBiointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment10.1038/s41467-019-13727-92041-1723https://doaj.org/article/9b1f08e6b5b442da8defad2bf3d2782c2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13727-9https://doaj.org/toc/2041-1723Oral microbiota delivery is an approach to treat and prevent disease but suffers from low retention and bioavailability. Here the authors report on a lipid coating to protect against environmental assault maintaining viability and bioactivity of the bacteria and demonstrate effective application in a colitis model.Zhenping CaoXinyue WangYan PangShanshan ChengJinyao LiuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Zhenping Cao
Xinyue Wang
Yan Pang
Shanshan Cheng
Jinyao Liu
Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment
description Oral microbiota delivery is an approach to treat and prevent disease but suffers from low retention and bioavailability. Here the authors report on a lipid coating to protect against environmental assault maintaining viability and bioactivity of the bacteria and demonstrate effective application in a colitis model.
format article
author Zhenping Cao
Xinyue Wang
Yan Pang
Shanshan Cheng
Jinyao Liu
author_facet Zhenping Cao
Xinyue Wang
Yan Pang
Shanshan Cheng
Jinyao Liu
author_sort Zhenping Cao
title Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment
title_short Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment
title_full Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment
title_fullStr Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment
title_full_unstemmed Biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment
title_sort biointerfacial self-assembly generates lipid membrane coated bacteria for enhanced oral delivery and treatment
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/9b1f08e6b5b442da8defad2bf3d2782c
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AT xinyuewang biointerfacialselfassemblygenerateslipidmembranecoatedbacteriaforenhancedoraldeliveryandtreatment
AT yanpang biointerfacialselfassemblygenerateslipidmembranecoatedbacteriaforenhancedoraldeliveryandtreatment
AT shanshancheng biointerfacialselfassemblygenerateslipidmembranecoatedbacteriaforenhancedoraldeliveryandtreatment
AT jinyaoliu biointerfacialselfassemblygenerateslipidmembranecoatedbacteriaforenhancedoraldeliveryandtreatment
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