A nitric oxide-releasing prodrug promotes apoptosis in human renal carcinoma cells: Involvement of reactive oxygen species

JS-K is a nitric oxide (NO)-releasing prodrug of the O2-arylated diazeniumdiolate group that shows pronounced cytotoxicity and antitumor properties in numerous cancer models, including in vitro as well as in vivo. Reactive oxygen species (ROS) induce carcinogenesis by altering the redox status, caus...

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Autores principales:	Xie Jindong, Chen Lieqian, Huang Dongqiang, Yue Weiwei, Chen Jingyu, Liu Chunxiao
Formato:	article
Lenguaje:	EN
Publicado:	De Gruyter 2021
Materias:	apoptosis ros js-k nitric oxide renal carcinoma cells Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/9b1f2229b9e34de4b3750fe6ec7edf22
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:9b1f2229b9e34de4b3750fe6ec7edf222021-12-05T14:10:43ZA nitric oxide-releasing prodrug promotes apoptosis in human renal carcinoma cells: Involvement of reactive oxygen species2391-542010.1515/chem-2020-0075https://doaj.org/article/9b1f2229b9e34de4b3750fe6ec7edf222021-05-01T00:00:00Zhttps://doi.org/10.1515/chem-2020-0075https://doaj.org/toc/2391-5420JS-K is a nitric oxide (NO)-releasing prodrug of the O2-arylated diazeniumdiolate group that shows pronounced cytotoxicity and antitumor properties in numerous cancer models, including in vitro as well as in vivo. Reactive oxygen species (ROS) induce carcinogenesis by altering the redox status, causing increment in vulnerability to oxidative stress.Xie JindongChen LieqianHuang DongqiangYue WeiweiChen JingyuLiu ChunxiaoDe Gruyterarticleapoptosisrosjs-knitric oxiderenal carcinoma cellsChemistryQD1-999ENOpen Chemistry, Vol 19, Iss 1, Pp 635-645 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	apoptosis ros js-k nitric oxide renal carcinoma cells Chemistry QD1-999
spellingShingle	apoptosis ros js-k nitric oxide renal carcinoma cells Chemistry QD1-999 Xie Jindong Chen Lieqian Huang Dongqiang Yue Weiwei Chen Jingyu Liu Chunxiao A nitric oxide-releasing prodrug promotes apoptosis in human renal carcinoma cells: Involvement of reactive oxygen species
description	JS-K is a nitric oxide (NO)-releasing prodrug of the O2-arylated diazeniumdiolate group that shows pronounced cytotoxicity and antitumor properties in numerous cancer models, including in vitro as well as in vivo. Reactive oxygen species (ROS) induce carcinogenesis by altering the redox status, causing increment in vulnerability to oxidative stress.
format	article
author	Xie Jindong Chen Lieqian Huang Dongqiang Yue Weiwei Chen Jingyu Liu Chunxiao
author_facet	Xie Jindong Chen Lieqian Huang Dongqiang Yue Weiwei Chen Jingyu Liu Chunxiao
author_sort	Xie Jindong
title	A nitric oxide-releasing prodrug promotes apoptosis in human renal carcinoma cells: Involvement of reactive oxygen species
title_short	A nitric oxide-releasing prodrug promotes apoptosis in human renal carcinoma cells: Involvement of reactive oxygen species
title_full	A nitric oxide-releasing prodrug promotes apoptosis in human renal carcinoma cells: Involvement of reactive oxygen species
title_fullStr	A nitric oxide-releasing prodrug promotes apoptosis in human renal carcinoma cells: Involvement of reactive oxygen species
title_full_unstemmed	A nitric oxide-releasing prodrug promotes apoptosis in human renal carcinoma cells: Involvement of reactive oxygen species
title_sort	nitric oxide-releasing prodrug promotes apoptosis in human renal carcinoma cells: involvement of reactive oxygen species
publisher	De Gruyter
publishDate	2021
url	https://doaj.org/article/9b1f2229b9e34de4b3750fe6ec7edf22
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A nitric oxide-releasing prodrug promotes apoptosis in human renal carcinoma cells: Involvement of reactive oxygen species

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