Contrast enhanced X-ray computed tomography imaging of amyloid plaques in Alzheimer disease rat model on lab based micro CT system

Abstract Amyloid plaques are small (~ 50 μm), highly-dense aggregates of amyloid beta (Aβ) protein in brain tissue, supposed to play a key role in pathogenesis of Alzheimer’s disease (AD). Plaques´ in vivo detection, spatial distribution and quantitative characterization could be an essential marker...

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Autores principales: Michaela Kavkova, Tomas Zikmund, Annu Kala, Jakub Salplachta, Stephanie L. Proskauer Pena, Josef Kaiser, Karel Jezek
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9b2736a730b74424bb8554ef8825cea9
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