Localized force application reveals mechanically sensitive domains of Piezo1

Piezo ion channels transduce mechanical forces into biological signals. Here, the authors use magnetic tweezers to pull specific regions of Piezo1, identifying mechanically sensitive domains that are essential for channel activation and inactivation.

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Auteurs principaux: Jason Wu, Raman Goyal, Jörg Grandl
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/9b2a3316a5b846f387db4b7f7d9a9f06
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