Development of a functional salivary gland tissue chip with potential for high-content drug screening

Song, Uchida, and Sharipol et al. develop functional tissue mimetics for mouse and human salivary glands by combining engineered extracellular matrices with microbubble array technology. The resulting tissue mimetics emulate phenotype and function of salivary glands and provide promise for high-cont...

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Autores principales:	Yuanhui Song, Hitoshi Uchida, Azmeer Sharipol, Lindsay Piraino, Jared A. Mereness, Matthew H. Ingalls, Jonathan Rebhahn, Shawn D. Newlands, Lisa A. DeLouise, Catherine E. Ovitt, Danielle S. W. Benoit
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/9b358e51fdcd44d791f1765e988cf0e6
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spelling	oai:doaj.org-article:9b358e51fdcd44d791f1765e988cf0e62021-12-02T17:05:10ZDevelopment of a functional salivary gland tissue chip with potential for high-content drug screening10.1038/s42003-021-01876-x2399-3642https://doaj.org/article/9b358e51fdcd44d791f1765e988cf0e62021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01876-xhttps://doaj.org/toc/2399-3642Song, Uchida, and Sharipol et al. develop functional tissue mimetics for mouse and human salivary glands by combining engineered extracellular matrices with microbubble array technology. The resulting tissue mimetics emulate phenotype and function of salivary glands and provide promise for high-content/throughput drug testing.Yuanhui SongHitoshi UchidaAzmeer SharipolLindsay PirainoJared A. MerenessMatthew H. IngallsJonathan RebhahnShawn D. NewlandsLisa A. DeLouiseCatherine E. OvittDanielle S. W. BenoitNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Yuanhui Song Hitoshi Uchida Azmeer Sharipol Lindsay Piraino Jared A. Mereness Matthew H. Ingalls Jonathan Rebhahn Shawn D. Newlands Lisa A. DeLouise Catherine E. Ovitt Danielle S. W. Benoit Development of a functional salivary gland tissue chip with potential for high-content drug screening
description	Song, Uchida, and Sharipol et al. develop functional tissue mimetics for mouse and human salivary glands by combining engineered extracellular matrices with microbubble array technology. The resulting tissue mimetics emulate phenotype and function of salivary glands and provide promise for high-content/throughput drug testing.
format	article
author	Yuanhui Song Hitoshi Uchida Azmeer Sharipol Lindsay Piraino Jared A. Mereness Matthew H. Ingalls Jonathan Rebhahn Shawn D. Newlands Lisa A. DeLouise Catherine E. Ovitt Danielle S. W. Benoit
author_facet	Yuanhui Song Hitoshi Uchida Azmeer Sharipol Lindsay Piraino Jared A. Mereness Matthew H. Ingalls Jonathan Rebhahn Shawn D. Newlands Lisa A. DeLouise Catherine E. Ovitt Danielle S. W. Benoit
author_sort	Yuanhui Song
title	Development of a functional salivary gland tissue chip with potential for high-content drug screening
title_short	Development of a functional salivary gland tissue chip with potential for high-content drug screening
title_full	Development of a functional salivary gland tissue chip with potential for high-content drug screening
title_fullStr	Development of a functional salivary gland tissue chip with potential for high-content drug screening
title_full_unstemmed	Development of a functional salivary gland tissue chip with potential for high-content drug screening
title_sort	development of a functional salivary gland tissue chip with potential for high-content drug screening
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9b358e51fdcd44d791f1765e988cf0e6
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Development of a functional salivary gland tissue chip with potential for high-content drug screening

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