Successful treatment of pulmonary mucormycosis caused by Rhizopus microsporus with posaconazole

Abstract Background Mucormycosis is a rare fungal infection occurring chiefly in the lung or the rhino-orbital-cerebral compartment, particularly in patients with immunodeficiency or diabetes mellitus. Among Mucorales fungi, Rhizopus spp. are the most common cause of mucormycosis. Case presentation...

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Autores principales:	F. Yuan, J. Chen, F. Liu, Y. C. Dang, Q. T. Kong, H. Sang
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Pulmonary mucormycosis Rhizopus microspores Diabetes mellitus Posaconazole Medicine R
Acceso en línea:	https://doaj.org/article/9b35f01eea724c22ace84b9549a5b95b
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spelling	oai:doaj.org-article:9b35f01eea724c22ace84b9549a5b95b2021-11-21T12:27:10ZSuccessful treatment of pulmonary mucormycosis caused by Rhizopus microsporus with posaconazole10.1186/s40001-021-00602-x2047-783Xhttps://doaj.org/article/9b35f01eea724c22ace84b9549a5b95b2021-11-01T00:00:00Zhttps://doi.org/10.1186/s40001-021-00602-xhttps://doaj.org/toc/2047-783XAbstract Background Mucormycosis is a rare fungal infection occurring chiefly in the lung or the rhino-orbital-cerebral compartment, particularly in patients with immunodeficiency or diabetes mellitus. Among Mucorales fungi, Rhizopus spp. are the most common cause of mucormycosis. Case presentation We report a case of pulmonary mucormycosis caused by Rhizopus microsporus in a young patient with diabetes but no other apparent risk factors. The diagnosis mainly relied on clinical manifestation, positive pulmonary tissue biopsy, and fungal culture. The patient was successfully treated with posaconazole oral suspension and remains asymptomatic at one-year follow-up. Conclusions Pulmonary mucormycosis is a life-threatening condition and posaconazole is an effective treatment for pulmonary mucormycosis caused by Rhizopus microspores.F. YuanJ. ChenF. LiuY. C. DangQ. T. KongH. SangBMCarticlePulmonary mucormycosisRhizopus microsporesDiabetes mellitusPosaconazoleMedicineRENEuropean Journal of Medical Research, Vol 26, Iss 1, Pp 1-4 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Pulmonary mucormycosis Rhizopus microspores Diabetes mellitus Posaconazole Medicine R
spellingShingle	Pulmonary mucormycosis Rhizopus microspores Diabetes mellitus Posaconazole Medicine R F. Yuan J. Chen F. Liu Y. C. Dang Q. T. Kong H. Sang Successful treatment of pulmonary mucormycosis caused by Rhizopus microsporus with posaconazole
description	Abstract Background Mucormycosis is a rare fungal infection occurring chiefly in the lung or the rhino-orbital-cerebral compartment, particularly in patients with immunodeficiency or diabetes mellitus. Among Mucorales fungi, Rhizopus spp. are the most common cause of mucormycosis. Case presentation We report a case of pulmonary mucormycosis caused by Rhizopus microsporus in a young patient with diabetes but no other apparent risk factors. The diagnosis mainly relied on clinical manifestation, positive pulmonary tissue biopsy, and fungal culture. The patient was successfully treated with posaconazole oral suspension and remains asymptomatic at one-year follow-up. Conclusions Pulmonary mucormycosis is a life-threatening condition and posaconazole is an effective treatment for pulmonary mucormycosis caused by Rhizopus microspores.
format	article
author	F. Yuan J. Chen F. Liu Y. C. Dang Q. T. Kong H. Sang
author_facet	F. Yuan J. Chen F. Liu Y. C. Dang Q. T. Kong H. Sang
author_sort	F. Yuan
title	Successful treatment of pulmonary mucormycosis caused by Rhizopus microsporus with posaconazole
title_short	Successful treatment of pulmonary mucormycosis caused by Rhizopus microsporus with posaconazole
title_full	Successful treatment of pulmonary mucormycosis caused by Rhizopus microsporus with posaconazole
title_fullStr	Successful treatment of pulmonary mucormycosis caused by Rhizopus microsporus with posaconazole
title_full_unstemmed	Successful treatment of pulmonary mucormycosis caused by Rhizopus microsporus with posaconazole
title_sort	successful treatment of pulmonary mucormycosis caused by rhizopus microsporus with posaconazole
publisher	BMC
publishDate	2021
url	https://doaj.org/article/9b35f01eea724c22ace84b9549a5b95b
work_keys_str_mv	AT fyuan successfultreatmentofpulmonarymucormycosiscausedbyrhizopusmicrosporuswithposaconazole AT jchen successfultreatmentofpulmonarymucormycosiscausedbyrhizopusmicrosporuswithposaconazole AT fliu successfultreatmentofpulmonarymucormycosiscausedbyrhizopusmicrosporuswithposaconazole AT ycdang successfultreatmentofpulmonarymucormycosiscausedbyrhizopusmicrosporuswithposaconazole AT qtkong successfultreatmentofpulmonarymucormycosiscausedbyrhizopusmicrosporuswithposaconazole AT hsang successfultreatmentofpulmonarymucormycosiscausedbyrhizopusmicrosporuswithposaconazole
_version_	1718419020464521216

Successful treatment of pulmonary mucormycosis caused by Rhizopus microsporus with posaconazole

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