Reviewing Potentially Inappropriate Medication in Hospitalized Patients Over 65 Using Explicit Criteria: A Systematic Literature Review

Hesah Alshammari, Eman Al-Saeed, Zamzam Ahmed, Zoe Aslanpour Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UKCorrespondence: Hesah Alshammari Email h.hesah-a-j-m-a-alshammari@herts.ac.ukAbstract: Potentially inappropri...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Alshammari H, Al-Saeed E, Ahmed Z, Aslanpour Z
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	older population adverse drug effects drug review tools pim Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9b383e5ff3554dcba769fab8aae4b05c
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:9b383e5ff3554dcba769fab8aae4b05c
record_format	dspace
spelling	oai:doaj.org-article:9b383e5ff3554dcba769fab8aae4b05c2021-11-04T19:00:26ZReviewing Potentially Inappropriate Medication in Hospitalized Patients Over 65 Using Explicit Criteria: A Systematic Literature Review1179-1365https://doaj.org/article/9b383e5ff3554dcba769fab8aae4b05c2021-11-01T00:00:00Zhttps://www.dovepress.com/reviewing-potentially-inappropriate-medication-in-hospitalized-patient-peer-reviewed-fulltext-article-DHPShttps://doaj.org/toc/1179-1365Hesah Alshammari, Eman Al-Saeed, Zamzam Ahmed, Zoe Aslanpour Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UKCorrespondence: Hesah Alshammari Email h.hesah-a-j-m-a-alshammari@herts.ac.ukAbstract: Potentially inappropriate medication (PIM) is a primary health concern affecting the quality of life of patients over 65. PIM is associated with adverse drug reactions including falls, increased healthcare costs, health services utilization and hospital admissions. Various strategies, clinical guidelines and tools (explicit and implicit) have been developed to tackle this health concern. Despite these efforts, evidence still indicates a high prevalence of PIM in the older adult population. This systematic review explored the practice of using explicit tools to review PIM in hospitalized patients and examined the outcomes of PIM reduction. A literature search was conducted in several databases from their inception to 2019. Original studies that had an interventional element using explicit criteria detecting PIM in hospitalized patients over 65 were included. Descriptive narrative synthesis was used to analyze the included studies. The literature search yielded 6116 articles; 25 quantitative studies were included in this systematic literature review. Twenty were prospective studies and five were retrospective. Approximately, 15,500 patients were included in the review. Various healthcare professionals were involved in reviewing PIM including physicians and hospital pharmacists. Several tools were used to review PIM for hospitalized patients over 65, most frequently Beer’s criteria and the STOPP/START tool. The reduction of PIM ranged from 3.5% up to 87%. The most common PIM were benzodiazepines and antipsychotics. This systematic review showed promising outcomes in terms of improving patient outcomes. However, the reduction of PIM varied in the studies, raising the question of the variance between hospitals in the explicit tools used for review. Additional studies need to be conducted to further investigate the outcomes of reviewing PIM at different levels, as well as assessing the cost-effectiveness of using explicit tools in reducing PIM.Keywords: older population, adverse drug effects, drug review tools, PIMAlshammari HAl-Saeed EAhmed ZAslanpour ZDove Medical Pressarticleolder populationadverse drug effectsdrug review toolspimMedicine (General)R5-920ENDrug, Healthcare and Patient Safety, Vol Volume 13, Pp 183-210 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	older population adverse drug effects drug review tools pim Medicine (General) R5-920
spellingShingle	older population adverse drug effects drug review tools pim Medicine (General) R5-920 Alshammari H Al-Saeed E Ahmed Z Aslanpour Z Reviewing Potentially Inappropriate Medication in Hospitalized Patients Over 65 Using Explicit Criteria: A Systematic Literature Review
description	Hesah Alshammari, Eman Al-Saeed, Zamzam Ahmed, Zoe Aslanpour Department of Clinical and Pharmaceutical Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UKCorrespondence: Hesah Alshammari Email h.hesah-a-j-m-a-alshammari@herts.ac.ukAbstract: Potentially inappropriate medication (PIM) is a primary health concern affecting the quality of life of patients over 65. PIM is associated with adverse drug reactions including falls, increased healthcare costs, health services utilization and hospital admissions. Various strategies, clinical guidelines and tools (explicit and implicit) have been developed to tackle this health concern. Despite these efforts, evidence still indicates a high prevalence of PIM in the older adult population. This systematic review explored the practice of using explicit tools to review PIM in hospitalized patients and examined the outcomes of PIM reduction. A literature search was conducted in several databases from their inception to 2019. Original studies that had an interventional element using explicit criteria detecting PIM in hospitalized patients over 65 were included. Descriptive narrative synthesis was used to analyze the included studies. The literature search yielded 6116 articles; 25 quantitative studies were included in this systematic literature review. Twenty were prospective studies and five were retrospective. Approximately, 15,500 patients were included in the review. Various healthcare professionals were involved in reviewing PIM including physicians and hospital pharmacists. Several tools were used to review PIM for hospitalized patients over 65, most frequently Beer’s criteria and the STOPP/START tool. The reduction of PIM ranged from 3.5% up to 87%. The most common PIM were benzodiazepines and antipsychotics. This systematic review showed promising outcomes in terms of improving patient outcomes. However, the reduction of PIM varied in the studies, raising the question of the variance between hospitals in the explicit tools used for review. Additional studies need to be conducted to further investigate the outcomes of reviewing PIM at different levels, as well as assessing the cost-effectiveness of using explicit tools in reducing PIM.Keywords: older population, adverse drug effects, drug review tools, PIM
format	article
author	Alshammari H Al-Saeed E Ahmed Z Aslanpour Z
author_facet	Alshammari H Al-Saeed E Ahmed Z Aslanpour Z
author_sort	Alshammari H
title	Reviewing Potentially Inappropriate Medication in Hospitalized Patients Over 65 Using Explicit Criteria: A Systematic Literature Review
title_short	Reviewing Potentially Inappropriate Medication in Hospitalized Patients Over 65 Using Explicit Criteria: A Systematic Literature Review
title_full	Reviewing Potentially Inappropriate Medication in Hospitalized Patients Over 65 Using Explicit Criteria: A Systematic Literature Review
title_fullStr	Reviewing Potentially Inappropriate Medication in Hospitalized Patients Over 65 Using Explicit Criteria: A Systematic Literature Review
title_full_unstemmed	Reviewing Potentially Inappropriate Medication in Hospitalized Patients Over 65 Using Explicit Criteria: A Systematic Literature Review
title_sort	reviewing potentially inappropriate medication in hospitalized patients over 65 using explicit criteria: a systematic literature review
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/9b383e5ff3554dcba769fab8aae4b05c
work_keys_str_mv	AT alshammarih reviewingpotentiallyinappropriatemedicationinhospitalizedpatientsover65usingexplicitcriteriaasystematicliteraturereview AT alsaeede reviewingpotentiallyinappropriatemedicationinhospitalizedpatientsover65usingexplicitcriteriaasystematicliteraturereview AT ahmedz reviewingpotentiallyinappropriatemedicationinhospitalizedpatientsover65usingexplicitcriteriaasystematicliteraturereview AT aslanpourz reviewingpotentiallyinappropriatemedicationinhospitalizedpatientsover65usingexplicitcriteriaasystematicliteraturereview
_version_	1718444666381139968

Reviewing Potentially Inappropriate Medication in Hospitalized Patients Over 65 Using Explicit Criteria: A Systematic Literature Review

Ejemplares similares