flDPnn: Accurate intrinsic disorder prediction with putative propensities of disorder functions

The authors present flDPnn, a computational tool for disorder and disorder function predictions from protein sequences. flDPnn was assessed with the data from the “Critical Assessment of Protein Intrinsic Disorder Prediction” experiment and on an independent and low-similarity test dataset, which sh...

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Autores principales:	Gang Hu, Akila Katuwawala, Kui Wang, Zhonghua Wu, Sina Ghadermarzi, Jianzhao Gao, Lukasz Kurgan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9b467e5b636944909f7d8cf830f43acb
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spelling	oai:doaj.org-article:9b467e5b636944909f7d8cf830f43acb2021-12-02T16:43:56ZflDPnn: Accurate intrinsic disorder prediction with putative propensities of disorder functions10.1038/s41467-021-24773-72041-1723https://doaj.org/article/9b467e5b636944909f7d8cf830f43acb2021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24773-7https://doaj.org/toc/2041-1723The authors present flDPnn, a computational tool for disorder and disorder function predictions from protein sequences. flDPnn was assessed with the data from the “Critical Assessment of Protein Intrinsic Disorder Prediction” experiment and on an independent and low-similarity test dataset, which show that flDPnn offers accurate predictions of disorder, fully disordered proteins and four common disorder functions.Gang HuAkila KatuwawalaKui WangZhonghua WuSina GhadermarziJianzhao GaoLukasz KurganNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gang Hu Akila Katuwawala Kui Wang Zhonghua Wu Sina Ghadermarzi Jianzhao Gao Lukasz Kurgan flDPnn: Accurate intrinsic disorder prediction with putative propensities of disorder functions
description	The authors present flDPnn, a computational tool for disorder and disorder function predictions from protein sequences. flDPnn was assessed with the data from the “Critical Assessment of Protein Intrinsic Disorder Prediction” experiment and on an independent and low-similarity test dataset, which show that flDPnn offers accurate predictions of disorder, fully disordered proteins and four common disorder functions.
format	article
author	Gang Hu Akila Katuwawala Kui Wang Zhonghua Wu Sina Ghadermarzi Jianzhao Gao Lukasz Kurgan
author_facet	Gang Hu Akila Katuwawala Kui Wang Zhonghua Wu Sina Ghadermarzi Jianzhao Gao Lukasz Kurgan
author_sort	Gang Hu
title	flDPnn: Accurate intrinsic disorder prediction with putative propensities of disorder functions
title_short	flDPnn: Accurate intrinsic disorder prediction with putative propensities of disorder functions
title_full	flDPnn: Accurate intrinsic disorder prediction with putative propensities of disorder functions
title_fullStr	flDPnn: Accurate intrinsic disorder prediction with putative propensities of disorder functions
title_full_unstemmed	flDPnn: Accurate intrinsic disorder prediction with putative propensities of disorder functions
title_sort	fldpnn: accurate intrinsic disorder prediction with putative propensities of disorder functions
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9b467e5b636944909f7d8cf830f43acb
work_keys_str_mv	AT ganghu fldpnnaccurateintrinsicdisorderpredictionwithputativepropensitiesofdisorderfunctions AT akilakatuwawala fldpnnaccurateintrinsicdisorderpredictionwithputativepropensitiesofdisorderfunctions AT kuiwang fldpnnaccurateintrinsicdisorderpredictionwithputativepropensitiesofdisorderfunctions AT zhonghuawu fldpnnaccurateintrinsicdisorderpredictionwithputativepropensitiesofdisorderfunctions AT sinaghadermarzi fldpnnaccurateintrinsicdisorderpredictionwithputativepropensitiesofdisorderfunctions AT jianzhaogao fldpnnaccurateintrinsicdisorderpredictionwithputativepropensitiesofdisorderfunctions AT lukaszkurgan fldpnnaccurateintrinsicdisorderpredictionwithputativepropensitiesofdisorderfunctions
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flDPnn: Accurate intrinsic disorder prediction with putative propensities of disorder functions

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