The Effect of Eight Weeks of Testosterone Enanthate Consumption on Oxidative Indicators of Kidney Tissue in Resistance Trained Rats

Introduction: Taking anabolic steroids can affect the state of oxidative stress in different tissues of the body such as kidneys. This study aimed to examine the effect of 8 weeks of resistance training with testosterone enanthate consumption on tissue oxidation indicators in male rats. Methods: In...

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Autores principales:	Masoumeh Mehrabi, Yaser Kazemzadeh, Ali Gorzi, Seyed Ali Hosseini, Saeid Sedaghati
Formato:	article
Lenguaje:	EN
Publicado:	Zabol University of Medical sciences 2020
Materias:	oxidative stress testosterone enanthate resistance training kidney Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9b46f97afb394c8cb0bb645f37e23e64
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spelling	oai:doaj.org-article:9b46f97afb394c8cb0bb645f37e23e642021-11-17T09:54:52ZThe Effect of Eight Weeks of Testosterone Enanthate Consumption on Oxidative Indicators of Kidney Tissue in Resistance Trained Rats2476-664X10.34172/ijbsm.2020.27https://doaj.org/article/9b46f97afb394c8cb0bb645f37e23e642020-12-01T00:00:00Zhttp://ijbsm.zbmu.ac.ir/PDF/ijbsm-21474https://doaj.org/toc/2476-664XIntroduction: Taking anabolic steroids can affect the state of oxidative stress in different tissues of the body such as kidneys. This study aimed to examine the effect of 8 weeks of resistance training with testosterone enanthate consumption on tissue oxidation indicators in male rats. Methods: In the current experimental study, 18 rats with an average weight of 250 ± 50 g were divided into 3 groups of 6 animals including: (1) control, (2) training, and (3) training + testosterone. Rats in the training and training + testosterone groups underwent resistance training for 8 weeks and 5 sessions per week. Also, rats in the training + testosterone group received 20 mg/kg of testosterone enanthate by intramuscular injection 3 days a week. The resistance training protocol consisted of climbing a 1-meter ladder 5 days a week (4 sets of 6 with a rest interval of 60 to 90 seconds) in which the weights were 60% of the rats’ body weights in the first week, and 20% of the body weight was added to the weights every week. One-way analysis of variance was used to analyze the research findings (P≤0.05). Results: Glutathione peroxidase (GPx) level in the training + testosterone group was significantly lower than the control group (P=0.007); however, there were no significant differences in malonaldehyde (MDA) (P=0.64) and superoxide dismutase (SOD) (P=0.29) levels between the research groups. Conclusion: It seems that testosterone consumption can be effective in increasing oxidative stress factors in the kidney tissue of resistance-trained rats.Masoumeh MehrabiYaser KazemzadehAli GorziSeyed Ali HosseiniSaeid SedaghatiZabol University of Medical sciencesarticleoxidative stress testosterone enanthate resistance training kidney Medicine (General)R5-920ENInternational Journal of Basic Science in Medicine, Vol 5, Iss 4, Pp 155-159 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	oxidative stress testosterone enanthate resistance training kidney Medicine (General) R5-920
spellingShingle	oxidative stress testosterone enanthate resistance training kidney Medicine (General) R5-920 Masoumeh Mehrabi Yaser Kazemzadeh Ali Gorzi Seyed Ali Hosseini Saeid Sedaghati The Effect of Eight Weeks of Testosterone Enanthate Consumption on Oxidative Indicators of Kidney Tissue in Resistance Trained Rats
description	Introduction: Taking anabolic steroids can affect the state of oxidative stress in different tissues of the body such as kidneys. This study aimed to examine the effect of 8 weeks of resistance training with testosterone enanthate consumption on tissue oxidation indicators in male rats. Methods: In the current experimental study, 18 rats with an average weight of 250 ± 50 g were divided into 3 groups of 6 animals including: (1) control, (2) training, and (3) training + testosterone. Rats in the training and training + testosterone groups underwent resistance training for 8 weeks and 5 sessions per week. Also, rats in the training + testosterone group received 20 mg/kg of testosterone enanthate by intramuscular injection 3 days a week. The resistance training protocol consisted of climbing a 1-meter ladder 5 days a week (4 sets of 6 with a rest interval of 60 to 90 seconds) in which the weights were 60% of the rats’ body weights in the first week, and 20% of the body weight was added to the weights every week. One-way analysis of variance was used to analyze the research findings (P≤0.05). Results: Glutathione peroxidase (GPx) level in the training + testosterone group was significantly lower than the control group (P=0.007); however, there were no significant differences in malonaldehyde (MDA) (P=0.64) and superoxide dismutase (SOD) (P=0.29) levels between the research groups. Conclusion: It seems that testosterone consumption can be effective in increasing oxidative stress factors in the kidney tissue of resistance-trained rats.
format	article
author	Masoumeh Mehrabi Yaser Kazemzadeh Ali Gorzi Seyed Ali Hosseini Saeid Sedaghati
author_facet	Masoumeh Mehrabi Yaser Kazemzadeh Ali Gorzi Seyed Ali Hosseini Saeid Sedaghati
author_sort	Masoumeh Mehrabi
title	The Effect of Eight Weeks of Testosterone Enanthate Consumption on Oxidative Indicators of Kidney Tissue in Resistance Trained Rats
title_short	The Effect of Eight Weeks of Testosterone Enanthate Consumption on Oxidative Indicators of Kidney Tissue in Resistance Trained Rats
title_full	The Effect of Eight Weeks of Testosterone Enanthate Consumption on Oxidative Indicators of Kidney Tissue in Resistance Trained Rats
title_fullStr	The Effect of Eight Weeks of Testosterone Enanthate Consumption on Oxidative Indicators of Kidney Tissue in Resistance Trained Rats
title_full_unstemmed	The Effect of Eight Weeks of Testosterone Enanthate Consumption on Oxidative Indicators of Kidney Tissue in Resistance Trained Rats
title_sort	effect of eight weeks of testosterone enanthate consumption on oxidative indicators of kidney tissue in resistance trained rats
publisher	Zabol University of Medical sciences
publishDate	2020
url	https://doaj.org/article/9b46f97afb394c8cb0bb645f37e23e64
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The Effect of Eight Weeks of Testosterone Enanthate Consumption on Oxidative Indicators of Kidney Tissue in Resistance Trained Rats

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