Matefin/SUN-1 phosphorylation is part of a surveillance mechanism to coordinate chromosome synapsis and recombination with meiotic progression and chromosome movement.
Faithful chromosome segregation during meiosis I depends on the establishment of a crossover between homologous chromosomes. This requires induction of DNA double-strand breaks (DSBs), alignment of homologs, homolog association by synapsis, and repair of DSBs via homologous recombination. The succes...
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Main Authors: | Alexander Woglar, Anahita Daryabeigi, Adele Adamo, Cornelia Habacher, Thomas Machacek, Adriana La Volpe, Verena Jantsch |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/9b5b1674afbf4cb18c1ec5b51a3de6d0 |
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