Matefin/SUN-1 phosphorylation is part of a surveillance mechanism to coordinate chromosome synapsis and recombination with meiotic progression and chromosome movement.

Faithful chromosome segregation during meiosis I depends on the establishment of a crossover between homologous chromosomes. This requires induction of DNA double-strand breaks (DSBs), alignment of homologs, homolog association by synapsis, and repair of DSBs via homologous recombination. The succes...

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Auteurs principaux: Alexander Woglar, Anahita Daryabeigi, Adele Adamo, Cornelia Habacher, Thomas Machacek, Adriana La Volpe, Verena Jantsch
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
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Accès en ligne:https://doaj.org/article/9b5b1674afbf4cb18c1ec5b51a3de6d0
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