Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle

Mitochondria produce high amounts of ATP to power myosin motors and sustained muscle contraction. Here, the authors show that during development, muscles coordinate the morphogenesis of their myofibrils directly with their mitochondria to optimize both for the physiological needs of each muscle-type...

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Autores principales: Jerome Avellaneda, Clement Rodier, Fabrice Daian, Nicolas Brouilly, Thomas Rival, Nuno Miguel Luis, Frank Schnorrer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9b5f30c12d544bb09b09704711b32445
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spelling oai:doaj.org-article:9b5f30c12d544bb09b09704711b324452021-12-02T14:37:27ZMyofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle10.1038/s41467-021-22058-72041-1723https://doaj.org/article/9b5f30c12d544bb09b09704711b324452021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22058-7https://doaj.org/toc/2041-1723Mitochondria produce high amounts of ATP to power myosin motors and sustained muscle contraction. Here, the authors show that during development, muscles coordinate the morphogenesis of their myofibrils directly with their mitochondria to optimize both for the physiological needs of each muscle-type.Jerome AvellanedaClement RodierFabrice DaianNicolas BrouillyThomas RivalNuno Miguel LuisFrank SchnorrerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Jerome Avellaneda
Clement Rodier
Fabrice Daian
Nicolas Brouilly
Thomas Rival
Nuno Miguel Luis
Frank Schnorrer
Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle
description Mitochondria produce high amounts of ATP to power myosin motors and sustained muscle contraction. Here, the authors show that during development, muscles coordinate the morphogenesis of their myofibrils directly with their mitochondria to optimize both for the physiological needs of each muscle-type.
format article
author Jerome Avellaneda
Clement Rodier
Fabrice Daian
Nicolas Brouilly
Thomas Rival
Nuno Miguel Luis
Frank Schnorrer
author_facet Jerome Avellaneda
Clement Rodier
Fabrice Daian
Nicolas Brouilly
Thomas Rival
Nuno Miguel Luis
Frank Schnorrer
author_sort Jerome Avellaneda
title Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle
title_short Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle
title_full Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle
title_fullStr Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle
title_full_unstemmed Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle
title_sort myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/9b5f30c12d544bb09b09704711b32445
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