Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle
Mitochondria produce high amounts of ATP to power myosin motors and sustained muscle contraction. Here, the authors show that during development, muscles coordinate the morphogenesis of their myofibrils directly with their mitochondria to optimize both for the physiological needs of each muscle-type...
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Nature Portfolio
2021
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oai:doaj.org-article:9b5f30c12d544bb09b09704711b324452021-12-02T14:37:27ZMyofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle10.1038/s41467-021-22058-72041-1723https://doaj.org/article/9b5f30c12d544bb09b09704711b324452021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22058-7https://doaj.org/toc/2041-1723Mitochondria produce high amounts of ATP to power myosin motors and sustained muscle contraction. Here, the authors show that during development, muscles coordinate the morphogenesis of their myofibrils directly with their mitochondria to optimize both for the physiological needs of each muscle-type.Jerome AvellanedaClement RodierFabrice DaianNicolas BrouillyThomas RivalNuno Miguel LuisFrank SchnorrerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021) |
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Science Q Jerome Avellaneda Clement Rodier Fabrice Daian Nicolas Brouilly Thomas Rival Nuno Miguel Luis Frank Schnorrer Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle |
description |
Mitochondria produce high amounts of ATP to power myosin motors and sustained muscle contraction. Here, the authors show that during development, muscles coordinate the morphogenesis of their myofibrils directly with their mitochondria to optimize both for the physiological needs of each muscle-type. |
format |
article |
author |
Jerome Avellaneda Clement Rodier Fabrice Daian Nicolas Brouilly Thomas Rival Nuno Miguel Luis Frank Schnorrer |
author_facet |
Jerome Avellaneda Clement Rodier Fabrice Daian Nicolas Brouilly Thomas Rival Nuno Miguel Luis Frank Schnorrer |
author_sort |
Jerome Avellaneda |
title |
Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle |
title_short |
Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle |
title_full |
Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle |
title_fullStr |
Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle |
title_full_unstemmed |
Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle |
title_sort |
myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/9b5f30c12d544bb09b09704711b32445 |
work_keys_str_mv |
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1718391021790822400 |