One-pot aminobenzylation of aldehydes with toluenes

Amines are common targets in synthetic chemistry as they often display biological activity. Here, the authors report a one-pot aminobenzylation of aldehydes with readily available toluenes in presence of a sodium amide derivative and a cesium salt additive generating an array of valuable 1,2-diaryle...

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Main Authors:	Zhiting Wang, Zhipeng Zheng, Xinyu Xu, Jianyou Mao, Patrick J. Walsh
Format:	article
Language:	EN
Published:	Nature Portfolio 2018
Subjects:	Science Q
Online Access:	https://doaj.org/article/9b6437b01ebf4f6ba01181e22c36f1fd
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spelling	oai:doaj.org-article:9b6437b01ebf4f6ba01181e22c36f1fd2021-12-02T16:56:35ZOne-pot aminobenzylation of aldehydes with toluenes10.1038/s41467-018-05638-y2041-1723https://doaj.org/article/9b6437b01ebf4f6ba01181e22c36f1fd2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05638-yhttps://doaj.org/toc/2041-1723Amines are common targets in synthetic chemistry as they often display biological activity. Here, the authors report a one-pot aminobenzylation of aldehydes with readily available toluenes in presence of a sodium amide derivative and a cesium salt additive generating an array of valuable 1,2-diarylethylamine compounds.Zhiting WangZhipeng ZhengXinyu XuJianyou MaoPatrick J. WalshNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Zhiting Wang Zhipeng Zheng Xinyu Xu Jianyou Mao Patrick J. Walsh One-pot aminobenzylation of aldehydes with toluenes
description	Amines are common targets in synthetic chemistry as they often display biological activity. Here, the authors report a one-pot aminobenzylation of aldehydes with readily available toluenes in presence of a sodium amide derivative and a cesium salt additive generating an array of valuable 1,2-diarylethylamine compounds.
format	article
author	Zhiting Wang Zhipeng Zheng Xinyu Xu Jianyou Mao Patrick J. Walsh
author_facet	Zhiting Wang Zhipeng Zheng Xinyu Xu Jianyou Mao Patrick J. Walsh
author_sort	Zhiting Wang
title	One-pot aminobenzylation of aldehydes with toluenes
title_short	One-pot aminobenzylation of aldehydes with toluenes
title_full	One-pot aminobenzylation of aldehydes with toluenes
title_fullStr	One-pot aminobenzylation of aldehydes with toluenes
title_full_unstemmed	One-pot aminobenzylation of aldehydes with toluenes
title_sort	one-pot aminobenzylation of aldehydes with toluenes
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/9b6437b01ebf4f6ba01181e22c36f1fd
work_keys_str_mv	AT zhitingwang onepotaminobenzylationofaldehydeswithtoluenes AT zhipengzheng onepotaminobenzylationofaldehydeswithtoluenes AT xinyuxu onepotaminobenzylationofaldehydeswithtoluenes AT jianyoumao onepotaminobenzylationofaldehydeswithtoluenes AT patrickjwalsh onepotaminobenzylationofaldehydeswithtoluenes
_version_	1718382815359270912

One-pot aminobenzylation of aldehydes with toluenes

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