Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor

Myeloid cells are implicated in the innate immune and inflammatory response during infection with Chlamydia trachomatis. Here the authors show the evasion of the neutrophil response to infection and concomitant induction of sterile immunity via the purinergic P2X7 receptor.

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Autores principales:	Chunfu Yang, Lei Lei, John W. Marshall Collins, Michael Briones, Li Ma, Gail L. Sturdevant, Hua Su, Anuj K. Kashyap, David Dorward, Kevin W. Bock, Ian N. Moore, Christine Bonner, Chih-Yu Chen, Craig A. Martens, Stacy Ricklefs, Masahiro Yamamoto, Kiyoshi Takeda, Yoichiro Iwakura, Grant McClarty, Harlan D. Caldwell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9b6d6afc6d5a40fdb29b81834b7b8934
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spelling	oai:doaj.org-article:9b6d6afc6d5a40fdb29b81834b7b89342021-12-02T15:31:37ZChlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor10.1038/s41467-021-25749-32041-1723https://doaj.org/article/9b6d6afc6d5a40fdb29b81834b7b89342021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25749-3https://doaj.org/toc/2041-1723Myeloid cells are implicated in the innate immune and inflammatory response during infection with Chlamydia trachomatis. Here the authors show the evasion of the neutrophil response to infection and concomitant induction of sterile immunity via the purinergic P2X7 receptor.Chunfu YangLei LeiJohn W. Marshall CollinsMichael BrionesLi MaGail L. SturdevantHua SuAnuj K. KashyapDavid DorwardKevin W. BockIan N. MooreChristine BonnerChih-Yu ChenCraig A. MartensStacy RicklefsMasahiro YamamotoKiyoshi TakedaYoichiro IwakuraGrant McClartyHarlan D. CaldwellNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chunfu Yang Lei Lei John W. Marshall Collins Michael Briones Li Ma Gail L. Sturdevant Hua Su Anuj K. Kashyap David Dorward Kevin W. Bock Ian N. Moore Christine Bonner Chih-Yu Chen Craig A. Martens Stacy Ricklefs Masahiro Yamamoto Kiyoshi Takeda Yoichiro Iwakura Grant McClarty Harlan D. Caldwell Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor
description	Myeloid cells are implicated in the innate immune and inflammatory response during infection with Chlamydia trachomatis. Here the authors show the evasion of the neutrophil response to infection and concomitant induction of sterile immunity via the purinergic P2X7 receptor.
format	article
author	Chunfu Yang Lei Lei John W. Marshall Collins Michael Briones Li Ma Gail L. Sturdevant Hua Su Anuj K. Kashyap David Dorward Kevin W. Bock Ian N. Moore Christine Bonner Chih-Yu Chen Craig A. Martens Stacy Ricklefs Masahiro Yamamoto Kiyoshi Takeda Yoichiro Iwakura Grant McClarty Harlan D. Caldwell
author_facet	Chunfu Yang Lei Lei John W. Marshall Collins Michael Briones Li Ma Gail L. Sturdevant Hua Su Anuj K. Kashyap David Dorward Kevin W. Bock Ian N. Moore Christine Bonner Chih-Yu Chen Craig A. Martens Stacy Ricklefs Masahiro Yamamoto Kiyoshi Takeda Yoichiro Iwakura Grant McClarty Harlan D. Caldwell
author_sort	Chunfu Yang
title	Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor
title_short	Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor
title_full	Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor
title_fullStr	Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor
title_full_unstemmed	Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor
title_sort	chlamydia evasion of neutrophil host defense results in nlrp3 dependent myeloid-mediated sterile inflammation through the purinergic p2x7 receptor
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9b6d6afc6d5a40fdb29b81834b7b8934
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Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor

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