Visible-light photoredox-catalyzed umpolung carboxylation of carbonyl compounds with CO2

Compounds bearing a carbonyl group, such as aldehydes and ketones, are important industrial chemicals and widespread in pharmaceuticals and natural products. Here, the authors report a strategy for visible-light photoredox-catalyzed umpolung carboxylation of diverse carbonyl compounds with CO2, to g...

Full description

Saved in:
Bibliographic Details
Main Authors: Guang-Mei Cao, Xin-Long Hu, Li-Li Liao, Si-Shun Yan, Lei Song, Jason J. Chruma, Li Gong, Da-Gang Yu
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Q
Online Access:https://doaj.org/article/9b7f948cac0f47a2b8b39d2e4feae65e
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Compounds bearing a carbonyl group, such as aldehydes and ketones, are important industrial chemicals and widespread in pharmaceuticals and natural products. Here, the authors report a strategy for visible-light photoredox-catalyzed umpolung carboxylation of diverse carbonyl compounds with CO2, to generate valuable α-hydroxycarboxylic acids.