Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid

Abstract Purpose: To highlight diagnostic challenges in patients with acquired vitelliform macular degeneration (AVMD) with subretinal fluid (SRF) and to examine the characteristics of image findings in patients with AVMD. Methods: In this retrospective review, the electronic medical record of 22 ey...

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Autores principales:	Joseph Juliano, Sagar Patel, Hossein Ameri
Formato:	article
Lenguaje:	EN
Publicado:	Knowledge E 2021
Materias:	age-related macular degeneration vitelliform macular degeneration vitelliform maculopathy Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/9b8373f398ee4efb886fb59fce5f5a13
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spelling	oai:doaj.org-article:9b8373f398ee4efb886fb59fce5f5a132021-11-09T08:05:35ZAcquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid2008-20102008-322X10.18502/jovr.v16i4.9748https://doaj.org/article/9b8373f398ee4efb886fb59fce5f5a132021-10-01T00:00:00Zhttps://doi.org/10.18502/jovr.v16i4.9748https://doaj.org/toc/2008-2010https://doaj.org/toc/2008-322XAbstract Purpose: To highlight diagnostic challenges in patients with acquired vitelliform macular degeneration (AVMD) with subretinal fluid (SRF) and to examine the characteristics of image findings in patients with AVMD. Methods: In this retrospective review, the electronic medical record of 22 eyes of 16 patients with AVMD was studied. The rates of SRF, drusen, pigment epithelial detachment (PED), and patient clinical information such as age, length of follow-up, and best-corrected visual acuity (BCVA) were assessed. Results: The mean age at diagnosis with AVMD was 72 years with a mean follow-up time of 29 months. Median BCVA 20/33 at presentation and 20/33 at final follow-up. Drusen was found in 13 of 22 eyes (59.1%), PEDs in 4 of 22 eyes (18.2%), and SRF in 10 of 22 eyes (45.5%) at some point during their follow-up. Of the 10 eyes with SRF, 70% were center involving, and recurrence occurred in 40%, all in the same location as the initial presentation of SRF. Three eyes received an anti-vascular endothelial growth factor injection for SRF. In 66% of cases receiving an injection, the fluid later relapsed and remitted without further injections during the course of follow-up. Conclusion: AVMD occurs in the same demographic as age-related macular degeneration (AMD) and has many common features. SRF in AVMD tends to be center involving and recurs usually in the same location as its origin. The use of anti-VEGF injections did not seem to improve SRF in contrast to the SRF seen in wet AMD. Proper differentiation of AVMD may prevent unnecessary long-term treatment with intravitreal anti-VEGF injections.Joseph JulianoSagar PatelHossein AmeriKnowledge Earticleage-related macular degenerationvitelliform macular degenerationvitelliform maculopathyOphthalmologyRE1-994ENJournal of Ophthalmic & Vision Research, Vol 16, Iss 4, Pp 582-591 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	age-related macular degeneration vitelliform macular degeneration vitelliform maculopathy Ophthalmology RE1-994
spellingShingle	age-related macular degeneration vitelliform macular degeneration vitelliform maculopathy Ophthalmology RE1-994 Joseph Juliano Sagar Patel Hossein Ameri Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid
description	Abstract Purpose: To highlight diagnostic challenges in patients with acquired vitelliform macular degeneration (AVMD) with subretinal fluid (SRF) and to examine the characteristics of image findings in patients with AVMD. Methods: In this retrospective review, the electronic medical record of 22 eyes of 16 patients with AVMD was studied. The rates of SRF, drusen, pigment epithelial detachment (PED), and patient clinical information such as age, length of follow-up, and best-corrected visual acuity (BCVA) were assessed. Results: The mean age at diagnosis with AVMD was 72 years with a mean follow-up time of 29 months. Median BCVA 20/33 at presentation and 20/33 at final follow-up. Drusen was found in 13 of 22 eyes (59.1%), PEDs in 4 of 22 eyes (18.2%), and SRF in 10 of 22 eyes (45.5%) at some point during their follow-up. Of the 10 eyes with SRF, 70% were center involving, and recurrence occurred in 40%, all in the same location as the initial presentation of SRF. Three eyes received an anti-vascular endothelial growth factor injection for SRF. In 66% of cases receiving an injection, the fluid later relapsed and remitted without further injections during the course of follow-up. Conclusion: AVMD occurs in the same demographic as age-related macular degeneration (AMD) and has many common features. SRF in AVMD tends to be center involving and recurs usually in the same location as its origin. The use of anti-VEGF injections did not seem to improve SRF in contrast to the SRF seen in wet AMD. Proper differentiation of AVMD may prevent unnecessary long-term treatment with intravitreal anti-VEGF injections.
format	article
author	Joseph Juliano Sagar Patel Hossein Ameri
author_facet	Joseph Juliano Sagar Patel Hossein Ameri
author_sort	Joseph Juliano
title	Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid
title_short	Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid
title_full	Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid
title_fullStr	Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid
title_full_unstemmed	Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid
title_sort	acquired vitelliform macular degeneration: characteristics and challenges of managing subretinal fluid
publisher	Knowledge E
publishDate	2021
url	https://doaj.org/article/9b8373f398ee4efb886fb59fce5f5a13
work_keys_str_mv	AT josephjuliano acquiredvitelliformmaculardegenerationcharacteristicsandchallengesofmanagingsubretinalfluid AT sagarpatel acquiredvitelliformmaculardegenerationcharacteristicsandchallengesofmanagingsubretinalfluid AT hosseinameri acquiredvitelliformmaculardegenerationcharacteristicsandchallengesofmanagingsubretinalfluid
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Acquired Vitelliform Macular Degeneration: Characteristics and Challenges of Managing Subretinal Fluid

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