Epidemiology profile and outcomes of oral potentially malignant disorders among different geographic regions of Taiwan: A retrospective observational nationwide population database study

Background: The malignant transformation of oral potentially malignant disorders (OPMDs) is a potential cause of oral cancers. However, epidemiological studies on malignant transformation of OPMDs are lacking. The present study is aimed to investigate the percentage of OPMD in the oral mucosal scree...

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Autores principales:	Sheng-Fu Chiu, Chung-Han Ho, Yi-Chen Chen, Li-Wha Wu, Yuh-Ling Chen, Jer-Horng Wu, Wei-Sheng Wu, Hui-Kun Hung, Wei-Fan Chiang
Formato:	article
Lenguaje:	EN
Publicado:	Wolters Kluwer Medknow Publications 2021
Materias:	oral cancer oral potentially malignant disorders oral mucosal screening city of taiwan region of taiwan rate of opmd per 1000 population malignant transformation Medicine R Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
Acceso en línea:	https://doaj.org/article/9b8574b47aa34defb031a6752e2afca5
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spelling	oai:doaj.org-article:9b8574b47aa34defb031a6752e2afca52021-11-12T10:24:36ZEpidemiology profile and outcomes of oral potentially malignant disorders among different geographic regions of Taiwan: A retrospective observational nationwide population database study1011-456410.4103/jmedsci.jmedsci_257_20https://doaj.org/article/9b8574b47aa34defb031a6752e2afca52021-01-01T00:00:00Zhttp://www.jmedscindmc.com/article.asp?issn=1011-4564;year=2021;volume=41;issue=6;spage=286;epage=294;aulast=Chiuhttps://doaj.org/toc/1011-4564Background: The malignant transformation of oral potentially malignant disorders (OPMDs) is a potential cause of oral cancers. However, epidemiological studies on malignant transformation of OPMDs are lacking. The present study is aimed to investigate the percentage of OPMD in the oral mucosal screening database and the malignant transformation (%) across different regions of Taiwan. Methods: We determined the cases of malignant transformation of OPMD to oral cancers during the 2-year follow-up by the oral mucosal screening database and the cancer registry database contained in the National Health Insurance Research Database. Patients with oral cancer history before OPMD diagnosis were excluded from the study. We collected data including clinical diagnosis, biopsy result, follow-up, and place of residence of the patient. The most widely used definition from the Council for Economic Planning and Development in Taiwan was used in this study for the classification into Southern, Northern, Eastern, and Western Taiwan regions. Differences in the malignant transformation (%) and ranking between regions were evaluated using analysis of variance test. Results: Chiayi city located in Southern Taiwan has the highest percentage of OPMD in oral screening citizen. The percentage of OPMD in the oral mucosal screening database was highest in Southern Taiwan and lowest in Eastern Taiwan; however, the malignant transformation (%) was highest in the Eastern Taiwan and lowest in Northern Taiwan. Conclusion: Dentists and otolaryngologists in Southern Taiwan, especially Chiayi city, should be cautious when screening the patient because of the high percentage of OPMD in oral mucosal screening database. The percentage of OPMD in the oral mucosal screening database and the malignant transformation (%) are different among the different regions in Taiwan. Further research is needed to clarify the reasons for the different malignant transformation (%) between regions.Sheng-Fu ChiuChung-Han HoYi-Chen ChenLi-Wha WuYuh-Ling ChenJer-Horng WuWei-Sheng WuHui-Kun HungWei-Fan ChiangWolters Kluwer Medknow Publicationsarticleoral canceroral potentially malignant disordersoral mucosal screeningcity of taiwanregion of taiwanrate of opmd per 1000 populationmalignant transformationMedicineRMedical emergencies. Critical care. Intensive care. First aidRC86-88.9ENJournal of Medical Sciences, Vol 41, Iss 6, Pp 286-294 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	oral cancer oral potentially malignant disorders oral mucosal screening city of taiwan region of taiwan rate of opmd per 1000 population malignant transformation Medicine R Medical emergencies. Critical care. Intensive care. First aid RC86-88.9
spellingShingle	oral cancer oral potentially malignant disorders oral mucosal screening city of taiwan region of taiwan rate of opmd per 1000 population malignant transformation Medicine R Medical emergencies. Critical care. Intensive care. First aid RC86-88.9 Sheng-Fu Chiu Chung-Han Ho Yi-Chen Chen Li-Wha Wu Yuh-Ling Chen Jer-Horng Wu Wei-Sheng Wu Hui-Kun Hung Wei-Fan Chiang Epidemiology profile and outcomes of oral potentially malignant disorders among different geographic regions of Taiwan: A retrospective observational nationwide population database study
description	Background: The malignant transformation of oral potentially malignant disorders (OPMDs) is a potential cause of oral cancers. However, epidemiological studies on malignant transformation of OPMDs are lacking. The present study is aimed to investigate the percentage of OPMD in the oral mucosal screening database and the malignant transformation (%) across different regions of Taiwan. Methods: We determined the cases of malignant transformation of OPMD to oral cancers during the 2-year follow-up by the oral mucosal screening database and the cancer registry database contained in the National Health Insurance Research Database. Patients with oral cancer history before OPMD diagnosis were excluded from the study. We collected data including clinical diagnosis, biopsy result, follow-up, and place of residence of the patient. The most widely used definition from the Council for Economic Planning and Development in Taiwan was used in this study for the classification into Southern, Northern, Eastern, and Western Taiwan regions. Differences in the malignant transformation (%) and ranking between regions were evaluated using analysis of variance test. Results: Chiayi city located in Southern Taiwan has the highest percentage of OPMD in oral screening citizen. The percentage of OPMD in the oral mucosal screening database was highest in Southern Taiwan and lowest in Eastern Taiwan; however, the malignant transformation (%) was highest in the Eastern Taiwan and lowest in Northern Taiwan. Conclusion: Dentists and otolaryngologists in Southern Taiwan, especially Chiayi city, should be cautious when screening the patient because of the high percentage of OPMD in oral mucosal screening database. The percentage of OPMD in the oral mucosal screening database and the malignant transformation (%) are different among the different regions in Taiwan. Further research is needed to clarify the reasons for the different malignant transformation (%) between regions.
format	article
author	Sheng-Fu Chiu Chung-Han Ho Yi-Chen Chen Li-Wha Wu Yuh-Ling Chen Jer-Horng Wu Wei-Sheng Wu Hui-Kun Hung Wei-Fan Chiang
author_facet	Sheng-Fu Chiu Chung-Han Ho Yi-Chen Chen Li-Wha Wu Yuh-Ling Chen Jer-Horng Wu Wei-Sheng Wu Hui-Kun Hung Wei-Fan Chiang
author_sort	Sheng-Fu Chiu
title	Epidemiology profile and outcomes of oral potentially malignant disorders among different geographic regions of Taiwan: A retrospective observational nationwide population database study
title_short	Epidemiology profile and outcomes of oral potentially malignant disorders among different geographic regions of Taiwan: A retrospective observational nationwide population database study
title_full	Epidemiology profile and outcomes of oral potentially malignant disorders among different geographic regions of Taiwan: A retrospective observational nationwide population database study
title_fullStr	Epidemiology profile and outcomes of oral potentially malignant disorders among different geographic regions of Taiwan: A retrospective observational nationwide population database study
title_full_unstemmed	Epidemiology profile and outcomes of oral potentially malignant disorders among different geographic regions of Taiwan: A retrospective observational nationwide population database study
title_sort	epidemiology profile and outcomes of oral potentially malignant disorders among different geographic regions of taiwan: a retrospective observational nationwide population database study
publisher	Wolters Kluwer Medknow Publications
publishDate	2021
url	https://doaj.org/article/9b8574b47aa34defb031a6752e2afca5
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Epidemiology profile and outcomes of oral potentially malignant disorders among different geographic regions of Taiwan: A retrospective observational nationwide population database study

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