Identification of ciguatoxins in a shark involved in a fatal food poisoning in the Indian Ocean
Abstract Severe food poisoning events after the consumption of sharks have been reported since the 1940s; however, there has been no clear understanding of their cause. Herein, we report for the first time the presence of ciguatoxins (CTXs) in sharks. The identification by mass spectrometry of CTXs,...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/9b858e1e61ac4257a918ccab63cf0df0 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:9b858e1e61ac4257a918ccab63cf0df0 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:9b858e1e61ac4257a918ccab63cf0df02021-12-02T16:08:00ZIdentification of ciguatoxins in a shark involved in a fatal food poisoning in the Indian Ocean10.1038/s41598-017-08682-82045-2322https://doaj.org/article/9b858e1e61ac4257a918ccab63cf0df02017-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-08682-8https://doaj.org/toc/2045-2322Abstract Severe food poisoning events after the consumption of sharks have been reported since the 1940s; however, there has been no clear understanding of their cause. Herein, we report for the first time the presence of ciguatoxins (CTXs) in sharks. The identification by mass spectrometry of CTXs, including two new analogues, in a bull shark (Carcharhinus leucas) that was consumed by humans, causing the poisoning and death of 11 people in Madagascar in 2013 is described. Typical neurotoxic ciguatera symptoms were recorded in patients, and toxicological assays on extracts of the shark demonstrated CTX-like activity. These results confirm this episode as a ciguatera poisoning event and expand the range of pelagic fish species that are involved in ciguatera in the Indian Ocean. Additionally, gambieric acid D, a molecule originally described in CTX-producing microalgae, was identified for the first time in fish. This finding can contribute to a better understanding of trophic relations within food webs. The present work confirms that consumption of sharks from the Indian Ocean should be considered a ciguatera risk, and actions should be taken to evaluate its magnitude and risk in order to manage shark fisheries.Jorge DiogèneLaia RevertéMaria Rambla-AlegreVanessa del RíoPablo de la IglesiaMònica CampàsOscar PalaciosCintia FloresJosep CaixachChristian RalijaonaIony RazanajatovoAgathe PirogHélène MagalonNathalie ArnichJean TurquetNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R Science Q |
| spellingShingle |
Medicine R Science Q Jorge Diogène Laia Reverté Maria Rambla-Alegre Vanessa del Río Pablo de la Iglesia Mònica Campàs Oscar Palacios Cintia Flores Josep Caixach Christian Ralijaona Iony Razanajatovo Agathe Pirog Hélène Magalon Nathalie Arnich Jean Turquet Identification of ciguatoxins in a shark involved in a fatal food poisoning in the Indian Ocean |
| description |
Abstract Severe food poisoning events after the consumption of sharks have been reported since the 1940s; however, there has been no clear understanding of their cause. Herein, we report for the first time the presence of ciguatoxins (CTXs) in sharks. The identification by mass spectrometry of CTXs, including two new analogues, in a bull shark (Carcharhinus leucas) that was consumed by humans, causing the poisoning and death of 11 people in Madagascar in 2013 is described. Typical neurotoxic ciguatera symptoms were recorded in patients, and toxicological assays on extracts of the shark demonstrated CTX-like activity. These results confirm this episode as a ciguatera poisoning event and expand the range of pelagic fish species that are involved in ciguatera in the Indian Ocean. Additionally, gambieric acid D, a molecule originally described in CTX-producing microalgae, was identified for the first time in fish. This finding can contribute to a better understanding of trophic relations within food webs. The present work confirms that consumption of sharks from the Indian Ocean should be considered a ciguatera risk, and actions should be taken to evaluate its magnitude and risk in order to manage shark fisheries. |
| format |
article |
| author |
Jorge Diogène Laia Reverté Maria Rambla-Alegre Vanessa del Río Pablo de la Iglesia Mònica Campàs Oscar Palacios Cintia Flores Josep Caixach Christian Ralijaona Iony Razanajatovo Agathe Pirog Hélène Magalon Nathalie Arnich Jean Turquet |
| author_facet |
Jorge Diogène Laia Reverté Maria Rambla-Alegre Vanessa del Río Pablo de la Iglesia Mònica Campàs Oscar Palacios Cintia Flores Josep Caixach Christian Ralijaona Iony Razanajatovo Agathe Pirog Hélène Magalon Nathalie Arnich Jean Turquet |
| author_sort |
Jorge Diogène |
| title |
Identification of ciguatoxins in a shark involved in a fatal food poisoning in the Indian Ocean |
| title_short |
Identification of ciguatoxins in a shark involved in a fatal food poisoning in the Indian Ocean |
| title_full |
Identification of ciguatoxins in a shark involved in a fatal food poisoning in the Indian Ocean |
| title_fullStr |
Identification of ciguatoxins in a shark involved in a fatal food poisoning in the Indian Ocean |
| title_full_unstemmed |
Identification of ciguatoxins in a shark involved in a fatal food poisoning in the Indian Ocean |
| title_sort |
identification of ciguatoxins in a shark involved in a fatal food poisoning in the indian ocean |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/9b858e1e61ac4257a918ccab63cf0df0 |
| work_keys_str_mv |
AT jorgediogene identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT laiareverte identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT mariaramblaalegre identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT vanessadelrio identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT pablodelaiglesia identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT monicacampas identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT oscarpalacios identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT cintiaflores identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT josepcaixach identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT christianralijaona identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT ionyrazanajatovo identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT agathepirog identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT helenemagalon identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT nathaliearnich identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean AT jeanturquet identificationofciguatoxinsinasharkinvolvedinafatalfoodpoisoningintheindianocean |
| _version_ |
1718384674059845632 |