Nanopore electric snapshots of an RNA tertiary folding pathway

While RNA folding is critical for its function, study of this process is challenging. Here, the authors combine nanopore single-molecule manipulation with theoretical analysis to follow the folding of an RNA pseudoknot, monitoring the intermediate states and the kinetics of their interconversion.

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Autores principales:	Xinyue Zhang, Dong Zhang, Chenhan Zhao, Kai Tian, Ruicheng Shi, Xiao Du, Andrew J. Burcke, Jing Wang, Shi-Jie Chen, Li-Qun Gu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9b898b5f4c654d6d85e942140b2f709b
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spelling	oai:doaj.org-article:9b898b5f4c654d6d85e942140b2f709b2021-12-02T14:42:28ZNanopore electric snapshots of an RNA tertiary folding pathway10.1038/s41467-017-01588-z2041-1723https://doaj.org/article/9b898b5f4c654d6d85e942140b2f709b2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01588-zhttps://doaj.org/toc/2041-1723While RNA folding is critical for its function, study of this process is challenging. Here, the authors combine nanopore single-molecule manipulation with theoretical analysis to follow the folding of an RNA pseudoknot, monitoring the intermediate states and the kinetics of their interconversion.Xinyue ZhangDong ZhangChenhan ZhaoKai TianRuicheng ShiXiao DuAndrew J. BurckeJing WangShi-Jie ChenLi-Qun GuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xinyue Zhang Dong Zhang Chenhan Zhao Kai Tian Ruicheng Shi Xiao Du Andrew J. Burcke Jing Wang Shi-Jie Chen Li-Qun Gu Nanopore electric snapshots of an RNA tertiary folding pathway
description	While RNA folding is critical for its function, study of this process is challenging. Here, the authors combine nanopore single-molecule manipulation with theoretical analysis to follow the folding of an RNA pseudoknot, monitoring the intermediate states and the kinetics of their interconversion.
format	article
author	Xinyue Zhang Dong Zhang Chenhan Zhao Kai Tian Ruicheng Shi Xiao Du Andrew J. Burcke Jing Wang Shi-Jie Chen Li-Qun Gu
author_facet	Xinyue Zhang Dong Zhang Chenhan Zhao Kai Tian Ruicheng Shi Xiao Du Andrew J. Burcke Jing Wang Shi-Jie Chen Li-Qun Gu
author_sort	Xinyue Zhang
title	Nanopore electric snapshots of an RNA tertiary folding pathway
title_short	Nanopore electric snapshots of an RNA tertiary folding pathway
title_full	Nanopore electric snapshots of an RNA tertiary folding pathway
title_fullStr	Nanopore electric snapshots of an RNA tertiary folding pathway
title_full_unstemmed	Nanopore electric snapshots of an RNA tertiary folding pathway
title_sort	nanopore electric snapshots of an rna tertiary folding pathway
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9b898b5f4c654d6d85e942140b2f709b
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Nanopore electric snapshots of an RNA tertiary folding pathway

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