Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6

There has been limited success in generating tissues from human induced pluripotent stem cells (hiPSCs). Here, the authors genetically engineer expression of the transcription factor Gata6 in a single isogenic hiPSC population resulting in complex tissue structures that exhibit liver bud-like proper...

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Autores principales:	Patrick Guye, Mohammad R. Ebrahimkhani, Nathan Kipniss, Jeremy J. Velazquez, Eldi Schoenfeld, Samira Kiani, Linda G. Griffith, Ron Weiss
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9b8be1df7dff49edbe97c27e4110a2e7
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spelling	oai:doaj.org-article:9b8be1df7dff49edbe97c27e4110a2e72021-12-02T16:49:41ZGenetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata610.1038/ncomms102432041-1723https://doaj.org/article/9b8be1df7dff49edbe97c27e4110a2e72016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10243https://doaj.org/toc/2041-1723There has been limited success in generating tissues from human induced pluripotent stem cells (hiPSCs). Here, the authors genetically engineer expression of the transcription factor Gata6 in a single isogenic hiPSC population resulting in complex tissue structures that exhibit liver bud-like properties.Patrick GuyeMohammad R. EbrahimkhaniNathan KipnissJeremy J. VelazquezEldi SchoenfeldSamira KianiLinda G. GriffithRon WeissNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Patrick Guye Mohammad R. Ebrahimkhani Nathan Kipniss Jeremy J. Velazquez Eldi Schoenfeld Samira Kiani Linda G. Griffith Ron Weiss Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6
description	There has been limited success in generating tissues from human induced pluripotent stem cells (hiPSCs). Here, the authors genetically engineer expression of the transcription factor Gata6 in a single isogenic hiPSC population resulting in complex tissue structures that exhibit liver bud-like properties.
format	article
author	Patrick Guye Mohammad R. Ebrahimkhani Nathan Kipniss Jeremy J. Velazquez Eldi Schoenfeld Samira Kiani Linda G. Griffith Ron Weiss
author_facet	Patrick Guye Mohammad R. Ebrahimkhani Nathan Kipniss Jeremy J. Velazquez Eldi Schoenfeld Samira Kiani Linda G. Griffith Ron Weiss
author_sort	Patrick Guye
title	Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6
title_short	Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6
title_full	Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6
title_fullStr	Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6
title_full_unstemmed	Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6
title_sort	genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using gata6
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/9b8be1df7dff49edbe97c27e4110a2e7
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Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6

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