Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6
There has been limited success in generating tissues from human induced pluripotent stem cells (hiPSCs). Here, the authors genetically engineer expression of the transcription factor Gata6 in a single isogenic hiPSC population resulting in complex tissue structures that exhibit liver bud-like proper...
Guardado en:
Autores principales: | Patrick Guye, Mohammad R. Ebrahimkhani, Nathan Kipniss, Jeremy J. Velazquez, Eldi Schoenfeld, Samira Kiani, Linda G. Griffith, Ron Weiss |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/9b8be1df7dff49edbe97c27e4110a2e7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Three-dimensional human placenta-like bud synthesized from induced pluripotent stem cells
por: Mai Sato, et al.
Publicado: (2021) -
Eukaryotic-Like Virus Budding in <italic toggle="yes">Archaea</italic>
por: Emmanuelle R. J. Quemin, et al.
Publicado: (2016) -
In vivo and ex vivo methods of growing a liver bud through tissue connection
por: Yusuke Yanagi, et al.
Publicado: (2017) -
GATA3 regulates FLG and FLG2 expression in human primary keratinocytes
por: Jana Zeitvogel, et al.
Publicado: (2017) -
Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes
por: Shayesteh R. Ferdosi, et al.
Publicado: (2019)