Convulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder

Jianbo Lai,1,2 Qiaoqiao Lu,3 Tingting Huang,3 Shaohua Hu,1,2 Yi Xu1,2 1Department of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine, 2Key Laboratory of Mental Disorder Management in Zhejiang Province, 3Department of Internal Medicine, Zhejiang University School of Med...

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Autores principales:	Lai J, Lu Q, Huang T, Hu S, Xu Y
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	quetiapine bipolar disorder hypotension convulsive syncope Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/9b96a4c46b7d4575addd8606326d1591
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spelling	oai:doaj.org-article:9b96a4c46b7d4575addd8606326d15912021-12-02T05:52:00ZConvulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder1178-2021https://doaj.org/article/9b96a4c46b7d4575addd8606326d15912017-07-01T00:00:00Zhttps://www.dovepress.com/convulsive-syncope-related-to-a-small-dose-of-quetiapine-in-an-adolesc-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Jianbo Lai,1,2 Qiaoqiao Lu,3 Tingting Huang,3 Shaohua Hu,1,2 Yi Xu1,2 1Department of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine, 2Key Laboratory of Mental Disorder Management in Zhejiang Province, 3Department of Internal Medicine, Zhejiang University School of Medicine, Hangzhou, China Abstract: Quetiapine, an atypical antipsychotic, has been extensively used in patients with bipolar disorder. Overdose of quetiapine can result in severe complications, such as coma, seizure, respiratory depression, arrhythmia, and even death. However, the paucity of toxicological evaluation in adolescence causes more potential risks in this population. Herein, we present a case of hypotension and convulsive syncope after exposure to a small dose of quetiapine in a 16-year-old who was diagnosed with bipolar disorder. After cessation of quetiapine, no additional convulsive movements were reported. This case indicates that even in young patients without predisposing factors, close monitoring of adverse effects should be warranted for safety concerns, especially at the initiation of quetiapine treatment. Keywords: quetiapine, bipolar disorder, hypotension, convulsive syncopeLai JLu QHuang THu SXu YDove Medical Pressarticlequetiapinebipolar disorderhypotensionconvulsive syncopeNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 13, Pp 1905-1908 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	quetiapine bipolar disorder hypotension convulsive syncope Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	quetiapine bipolar disorder hypotension convulsive syncope Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Lai J Lu Q Huang T Hu S Xu Y Convulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder
description	Jianbo Lai,1,2 Qiaoqiao Lu,3 Tingting Huang,3 Shaohua Hu,1,2 Yi Xu1,2 1Department of Psychiatry, First Affiliated Hospital, Zhejiang University School of Medicine, 2Key Laboratory of Mental Disorder Management in Zhejiang Province, 3Department of Internal Medicine, Zhejiang University School of Medicine, Hangzhou, China Abstract: Quetiapine, an atypical antipsychotic, has been extensively used in patients with bipolar disorder. Overdose of quetiapine can result in severe complications, such as coma, seizure, respiratory depression, arrhythmia, and even death. However, the paucity of toxicological evaluation in adolescence causes more potential risks in this population. Herein, we present a case of hypotension and convulsive syncope after exposure to a small dose of quetiapine in a 16-year-old who was diagnosed with bipolar disorder. After cessation of quetiapine, no additional convulsive movements were reported. This case indicates that even in young patients without predisposing factors, close monitoring of adverse effects should be warranted for safety concerns, especially at the initiation of quetiapine treatment. Keywords: quetiapine, bipolar disorder, hypotension, convulsive syncope
format	article
author	Lai J Lu Q Huang T Hu S Xu Y
author_facet	Lai J Lu Q Huang T Hu S Xu Y
author_sort	Lai J
title	Convulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder
title_short	Convulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder
title_full	Convulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder
title_fullStr	Convulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder
title_full_unstemmed	Convulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder
title_sort	convulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/9b96a4c46b7d4575addd8606326d1591
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Convulsive syncope related to a small dose of quetiapine in an adolescent with bipolar disorder

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