Immune phenotype and body condition in roe deer: individuals with high body condition have different, not stronger immunity.

An efficient immunity is necessary for host survival, but entails energetic costs. When energy is limited, immunocompetence and body condition should co-vary positively among individuals and, depending on body condition, individuals should allocate more either in innate immunity or in adaptive respo...

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Autores principales:	Emmanuelle Gilot-Fromont, Maël Jégo, Christophe Bonenfant, Philippe Gibert, Benoit Rannou, François Klein, Jean-Michel Gaillard
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9b9ba56defc54171b14624d16ebcc020
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spelling	oai:doaj.org-article:9b9ba56defc54171b14624d16ebcc0202021-11-18T07:04:53ZImmune phenotype and body condition in roe deer: individuals with high body condition have different, not stronger immunity.1932-620310.1371/journal.pone.0045576https://doaj.org/article/9b9ba56defc54171b14624d16ebcc0202012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23029110/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203An efficient immunity is necessary for host survival, but entails energetic costs. When energy is limited, immunocompetence and body condition should co-vary positively among individuals and, depending on body condition, individuals should allocate more either in innate immunity or in adaptive response. We tested whether immune phenotype depends on body condition in large mammals, using data from two contrasted populations of roe deer Capreolus capreolus in France. Roe deer living at Chizé, a forest with poor habitat quality, were expected to show lower values for body condition and immune parameters than roe deer at Trois Fontaines, a forest with high habitat quality. From 285 blood samples collected between December 2009 and March 2011, we measured seven metabolic parameters and ten immunological parameters. A Principal Component Analysis showed that all indicators of body condition co-varied positively and were lowest at Chizé. Several immunological indicators correlated to body condition and differed between Trois Fontaines and Chizé. However, high body condition was not associated to a high average level of immunocompetence, but instead to high levels of indicators of acute inflammatory innate response, while low body condition was associated to high levels of monocytes and lymphocytes, possibly reflecting adaptive immunity. Limited data suggest that the difference between populations was not related to the presence of specific parasite species, however parasite exposure and stress have to be investigated to gain a more complete understanding of the determinants of immunity.Emmanuelle Gilot-FromontMaël JégoChristophe BonenfantPhilippe GibertBenoit RannouFrançois KleinJean-Michel GaillardPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 9, p e45576 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Emmanuelle Gilot-Fromont Maël Jégo Christophe Bonenfant Philippe Gibert Benoit Rannou François Klein Jean-Michel Gaillard Immune phenotype and body condition in roe deer: individuals with high body condition have different, not stronger immunity.
description	An efficient immunity is necessary for host survival, but entails energetic costs. When energy is limited, immunocompetence and body condition should co-vary positively among individuals and, depending on body condition, individuals should allocate more either in innate immunity or in adaptive response. We tested whether immune phenotype depends on body condition in large mammals, using data from two contrasted populations of roe deer Capreolus capreolus in France. Roe deer living at Chizé, a forest with poor habitat quality, were expected to show lower values for body condition and immune parameters than roe deer at Trois Fontaines, a forest with high habitat quality. From 285 blood samples collected between December 2009 and March 2011, we measured seven metabolic parameters and ten immunological parameters. A Principal Component Analysis showed that all indicators of body condition co-varied positively and were lowest at Chizé. Several immunological indicators correlated to body condition and differed between Trois Fontaines and Chizé. However, high body condition was not associated to a high average level of immunocompetence, but instead to high levels of indicators of acute inflammatory innate response, while low body condition was associated to high levels of monocytes and lymphocytes, possibly reflecting adaptive immunity. Limited data suggest that the difference between populations was not related to the presence of specific parasite species, however parasite exposure and stress have to be investigated to gain a more complete understanding of the determinants of immunity.
format	article
author	Emmanuelle Gilot-Fromont Maël Jégo Christophe Bonenfant Philippe Gibert Benoit Rannou François Klein Jean-Michel Gaillard
author_facet	Emmanuelle Gilot-Fromont Maël Jégo Christophe Bonenfant Philippe Gibert Benoit Rannou François Klein Jean-Michel Gaillard
author_sort	Emmanuelle Gilot-Fromont
title	Immune phenotype and body condition in roe deer: individuals with high body condition have different, not stronger immunity.
title_short	Immune phenotype and body condition in roe deer: individuals with high body condition have different, not stronger immunity.
title_full	Immune phenotype and body condition in roe deer: individuals with high body condition have different, not stronger immunity.
title_fullStr	Immune phenotype and body condition in roe deer: individuals with high body condition have different, not stronger immunity.
title_full_unstemmed	Immune phenotype and body condition in roe deer: individuals with high body condition have different, not stronger immunity.
title_sort	immune phenotype and body condition in roe deer: individuals with high body condition have different, not stronger immunity.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/9b9ba56defc54171b14624d16ebcc020
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Immune phenotype and body condition in roe deer: individuals with high body condition have different, not stronger immunity.

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