The Location of the Deepest Point of the Eyeball Determines the Optic Disc Configuration

Abstract Tilted and rotated appearances are hallmarks of the myopic optic disc. As the eyeball grows axially, the posterior pole elongates not only globally but in a localized manner as well. In this process, the optic disc is pulled towards the deepest point of the elongated eyeball, which might re...

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Autores principales:	Yong Chan Kim, Younhea Jung, Hae-Young Lopilly Park, Chan Kee Park
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9b9d45a083964006b180f865f6b1df53
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spelling	oai:doaj.org-article:9b9d45a083964006b180f865f6b1df532021-12-02T15:06:10ZThe Location of the Deepest Point of the Eyeball Determines the Optic Disc Configuration10.1038/s41598-017-06072-82045-2322https://doaj.org/article/9b9d45a083964006b180f865f6b1df532017-07-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-06072-8https://doaj.org/toc/2045-2322Abstract Tilted and rotated appearances are hallmarks of the myopic optic disc. As the eyeball grows axially, the posterior pole elongates not only globally but in a localized manner as well. In this process, the optic disc is pulled towards the deepest point of the elongated eyeball, which might result in a change in optic disc configuration. Thus, we hypothesized that analyzing the variation of posterior pole contour can play a major role in understanding optic disc configuration in myopic subjects. By analyzing consecutive images of swept source OCT coronal sections at the posterior pole, the deepest interface between Bruch’s membrane and the choroid could be identified as the deepest point of the eyeball (DPE). The location and the properties of the DPE differed significantly between the 125 eyes of non-glaucomatous myopic group and the 40 eyes of non-glaucomatous emmetropic group classified based on 24 mm axial length. The results suggested that the larger disc to DPE angle and the larger disc to DPE depth strongly predicts the optic disc torsion degree and the optic disc tilt. Our findings suggest that identifying the posterior pole profile plays a major role in understanding the optic disc alterations found in myopic subjects.Yong Chan KimYounhea JungHae-Young Lopilly ParkChan Kee ParkNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yong Chan Kim Younhea Jung Hae-Young Lopilly Park Chan Kee Park The Location of the Deepest Point of the Eyeball Determines the Optic Disc Configuration
description	Abstract Tilted and rotated appearances are hallmarks of the myopic optic disc. As the eyeball grows axially, the posterior pole elongates not only globally but in a localized manner as well. In this process, the optic disc is pulled towards the deepest point of the elongated eyeball, which might result in a change in optic disc configuration. Thus, we hypothesized that analyzing the variation of posterior pole contour can play a major role in understanding optic disc configuration in myopic subjects. By analyzing consecutive images of swept source OCT coronal sections at the posterior pole, the deepest interface between Bruch’s membrane and the choroid could be identified as the deepest point of the eyeball (DPE). The location and the properties of the DPE differed significantly between the 125 eyes of non-glaucomatous myopic group and the 40 eyes of non-glaucomatous emmetropic group classified based on 24 mm axial length. The results suggested that the larger disc to DPE angle and the larger disc to DPE depth strongly predicts the optic disc torsion degree and the optic disc tilt. Our findings suggest that identifying the posterior pole profile plays a major role in understanding the optic disc alterations found in myopic subjects.
format	article
author	Yong Chan Kim Younhea Jung Hae-Young Lopilly Park Chan Kee Park
author_facet	Yong Chan Kim Younhea Jung Hae-Young Lopilly Park Chan Kee Park
author_sort	Yong Chan Kim
title	The Location of the Deepest Point of the Eyeball Determines the Optic Disc Configuration
title_short	The Location of the Deepest Point of the Eyeball Determines the Optic Disc Configuration
title_full	The Location of the Deepest Point of the Eyeball Determines the Optic Disc Configuration
title_fullStr	The Location of the Deepest Point of the Eyeball Determines the Optic Disc Configuration
title_full_unstemmed	The Location of the Deepest Point of the Eyeball Determines the Optic Disc Configuration
title_sort	location of the deepest point of the eyeball determines the optic disc configuration
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/9b9d45a083964006b180f865f6b1df53
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The Location of the Deepest Point of the Eyeball Determines the Optic Disc Configuration

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