The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection

Darko Duplancic,1 Marijan Cesarik,2 Nikola Kolja Poljak,3 Maja Radman,4 Vedran Kovacic,5 Josipa Radic,5 Veljko Rogosic61Department of Cardiology, School of Medicine in Split, University Hospital Split, Split, Croatia; 2Department for Neurology, County General Hospital Pozega, Pozega, Croatia; 3Depar...

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Autores principales:	Duplancic D, Cesarik M, Poljak NK, Radman M, Kovacic V, Radic J, Rogosic V
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	paricalcitol vitamin D cardio-renal syndrome Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/9ba1c67f428546559eb8d2127610992a
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spelling	oai:doaj.org-article:9ba1c67f428546559eb8d2127610992a2021-12-02T02:55:25ZThe influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection1178-1998https://doaj.org/article/9ba1c67f428546559eb8d2127610992a2013-02-01T00:00:00Zhttps://www.dovepress.com/the-influence-of-selective-vitamin-d-receptor-activator-paricalcitol-o-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Darko Duplancic,1 Marijan Cesarik,2 Nikola Kolja Poljak,3 Maja Radman,4 Vedran Kovacic,5 Josipa Radic,5 Veljko Rogosic61Department of Cardiology, School of Medicine in Split, University Hospital Split, Split, Croatia; 2Department for Neurology, County General Hospital Pozega, Pozega, Croatia; 3Department of Otorhinolaryngology, 4Department of Endocrinology, 5Department of Nephrology, 6Department of Ophthalmology, School of Medicine in Split, University Hospital Split, Split, CroatiaAbstract: The ubiquitous distribution of vitamin D receptors in the human body is responsible for the pleiotropic effects of vitamin D-receptor activation. We discuss the possible beneficial effects of a selective activator of vitamin D receptor, paricalcitol, on the cardiovascular system in chronic heart failure patients and chronic kidney patients, in light of new trials. Paricalcitol should provide additional clinical benefits over the standard treatment for chronic kidney and heart failure, especially in cases of cardiorenal syndrome.Keywords: vitamin D deficiency, cardiovascular system, albuminuria, inflammationDuplancic DCesarik MPoljak NKRadman MKovacic VRadic JRogosic VDove Medical Pressarticleparicalcitolvitamin Dcardio-renal syndromeGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 8, Pp 149-156 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	paricalcitol vitamin D cardio-renal syndrome Geriatrics RC952-954.6
spellingShingle	paricalcitol vitamin D cardio-renal syndrome Geriatrics RC952-954.6 Duplancic D Cesarik M Poljak NK Radman M Kovacic V Radic J Rogosic V The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
description	Darko Duplancic,1 Marijan Cesarik,2 Nikola Kolja Poljak,3 Maja Radman,4 Vedran Kovacic,5 Josipa Radic,5 Veljko Rogosic61Department of Cardiology, School of Medicine in Split, University Hospital Split, Split, Croatia; 2Department for Neurology, County General Hospital Pozega, Pozega, Croatia; 3Department of Otorhinolaryngology, 4Department of Endocrinology, 5Department of Nephrology, 6Department of Ophthalmology, School of Medicine in Split, University Hospital Split, Split, CroatiaAbstract: The ubiquitous distribution of vitamin D receptors in the human body is responsible for the pleiotropic effects of vitamin D-receptor activation. We discuss the possible beneficial effects of a selective activator of vitamin D receptor, paricalcitol, on the cardiovascular system in chronic heart failure patients and chronic kidney patients, in light of new trials. Paricalcitol should provide additional clinical benefits over the standard treatment for chronic kidney and heart failure, especially in cases of cardiorenal syndrome.Keywords: vitamin D deficiency, cardiovascular system, albuminuria, inflammation
format	article
author	Duplancic D Cesarik M Poljak NK Radman M Kovacic V Radic J Rogosic V
author_facet	Duplancic D Cesarik M Poljak NK Radman M Kovacic V Radic J Rogosic V
author_sort	Duplancic D
title	The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
title_short	The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
title_full	The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
title_fullStr	The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
title_full_unstemmed	The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection
title_sort	influence of selective vitamin d receptor activator paricalcitol on cardiovascular system and cardiorenal protection
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/9ba1c67f428546559eb8d2127610992a
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The influence of selective vitamin D receptor activator paricalcitol on cardiovascular system and cardiorenal protection

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