A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries

Accurate treatment of traumatic brain injuries, a leading cause of neurological disability and death in young people, is hampered by poor accumulation of drugs in the brain. Here, the authors describe a tetrapeptide that can efficiently target brain injuries and deliver therapeutic or diagnostic pay...

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Autores principales:	Aman P. Mann, Pablo Scodeller, Sazid Hussain, Jinmyoung Joo, Ester Kwon, Gary B. Braun, Tarmo Mölder, Zhi-Gang She, Venkata Ramana Kotamraju, Barbara Ranscht, Stan Krajewski, Tambet Teesalu, Sangeeta Bhatia, Michael J. Sailor, Erkki Ruoslahti
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9ba4b22334aa479f9406152857335901
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spelling	oai:doaj.org-article:9ba4b22334aa479f94061528573359012021-12-02T17:31:20ZA peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries10.1038/ncomms119802041-1723https://doaj.org/article/9ba4b22334aa479f94061528573359012016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11980https://doaj.org/toc/2041-1723Accurate treatment of traumatic brain injuries, a leading cause of neurological disability and death in young people, is hampered by poor accumulation of drugs in the brain. Here, the authors describe a tetrapeptide that can efficiently target brain injuries and deliver therapeutic or diagnostic payload.Aman P. MannPablo ScodellerSazid HussainJinmyoung JooEster KwonGary B. BraunTarmo MölderZhi-Gang SheVenkata Ramana KotamrajuBarbara RanschtStan KrajewskiTambet TeesaluSangeeta BhatiaMichael J. SailorErkki RuoslahtiNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aman P. Mann Pablo Scodeller Sazid Hussain Jinmyoung Joo Ester Kwon Gary B. Braun Tarmo Mölder Zhi-Gang She Venkata Ramana Kotamraju Barbara Ranscht Stan Krajewski Tambet Teesalu Sangeeta Bhatia Michael J. Sailor Erkki Ruoslahti A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries
description	Accurate treatment of traumatic brain injuries, a leading cause of neurological disability and death in young people, is hampered by poor accumulation of drugs in the brain. Here, the authors describe a tetrapeptide that can efficiently target brain injuries and deliver therapeutic or diagnostic payload.
format	article
author	Aman P. Mann Pablo Scodeller Sazid Hussain Jinmyoung Joo Ester Kwon Gary B. Braun Tarmo Mölder Zhi-Gang She Venkata Ramana Kotamraju Barbara Ranscht Stan Krajewski Tambet Teesalu Sangeeta Bhatia Michael J. Sailor Erkki Ruoslahti
author_facet	Aman P. Mann Pablo Scodeller Sazid Hussain Jinmyoung Joo Ester Kwon Gary B. Braun Tarmo Mölder Zhi-Gang She Venkata Ramana Kotamraju Barbara Ranscht Stan Krajewski Tambet Teesalu Sangeeta Bhatia Michael J. Sailor Erkki Ruoslahti
author_sort	Aman P. Mann
title	A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries
title_short	A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries
title_full	A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries
title_fullStr	A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries
title_full_unstemmed	A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries
title_sort	peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/9ba4b22334aa479f9406152857335901
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A peptide for targeted, systemic delivery of imaging and therapeutic compounds into acute brain injuries

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