IL-33 is produced by colon fibroblasts and differentially regulated in acute and chronic murine colitis

Abstract IL-33 is upregulated in ulcerative colitis and has a protective role in chemically-induced acute murine colitis. We aimed to determine whether IL-33 influences Il10 −/− chronic colitis and its cellular source in health and during colitis. Il10 −/− Il33 −/− and Il10 −/− Il33 +/+ littermates...

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Autores principales: Amanda Waddell, Jefferson E. Vallance, Sejal Fox, Michael J. Rosen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9ba6bf1031684756b61c33a2778032d4
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