Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy
Food allergy is an increasing public health problem. In a genome-wide scan of children diagnosed by oral food challenge, Marenholz et al. find new genetic associations underlying food allergy, implicating the immune system and the epithelial barrier.
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2017
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/9babf9e0239a43b69d6b7286939ba997 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:9babf9e0239a43b69d6b7286939ba997 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:9babf9e0239a43b69d6b7286939ba9972021-12-02T14:40:37ZGenome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy10.1038/s41467-017-01220-02041-1723https://doaj.org/article/9babf9e0239a43b69d6b7286939ba9972017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01220-0https://doaj.org/toc/2041-1723Food allergy is an increasing public health problem. In a genome-wide scan of children diagnosed by oral food challenge, Marenholz et al. find new genetic associations underlying food allergy, implicating the immune system and the epithelial barrier.Ingo MarenholzSarah GroscheBirgit KalbFranz RüschendorfKatharina BlümchenRupert SchlagsNeda HarandiMareike PriceGesine HansenJürgen SeidenbergHolger RöblitzSongül YürekSebastian TschirnerXiumei HongXiaobin WangGeorg HomuthCarsten O. SchmidtMarkus M. NöthenNorbert HübnerBodo NiggemannKirsten BeyerYoung-Ae LeeNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Ingo Marenholz Sarah Grosche Birgit Kalb Franz Rüschendorf Katharina Blümchen Rupert Schlags Neda Harandi Mareike Price Gesine Hansen Jürgen Seidenberg Holger Röblitz Songül Yürek Sebastian Tschirner Xiumei Hong Xiaobin Wang Georg Homuth Carsten O. Schmidt Markus M. Nöthen Norbert Hübner Bodo Niggemann Kirsten Beyer Young-Ae Lee Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy |
| description |
Food allergy is an increasing public health problem. In a genome-wide scan of children diagnosed by oral food challenge, Marenholz et al. find new genetic associations underlying food allergy, implicating the immune system and the epithelial barrier. |
| format |
article |
| author |
Ingo Marenholz Sarah Grosche Birgit Kalb Franz Rüschendorf Katharina Blümchen Rupert Schlags Neda Harandi Mareike Price Gesine Hansen Jürgen Seidenberg Holger Röblitz Songül Yürek Sebastian Tschirner Xiumei Hong Xiaobin Wang Georg Homuth Carsten O. Schmidt Markus M. Nöthen Norbert Hübner Bodo Niggemann Kirsten Beyer Young-Ae Lee |
| author_facet |
Ingo Marenholz Sarah Grosche Birgit Kalb Franz Rüschendorf Katharina Blümchen Rupert Schlags Neda Harandi Mareike Price Gesine Hansen Jürgen Seidenberg Holger Röblitz Songül Yürek Sebastian Tschirner Xiumei Hong Xiaobin Wang Georg Homuth Carsten O. Schmidt Markus M. Nöthen Norbert Hübner Bodo Niggemann Kirsten Beyer Young-Ae Lee |
| author_sort |
Ingo Marenholz |
| title |
Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy |
| title_short |
Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy |
| title_full |
Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy |
| title_fullStr |
Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy |
| title_full_unstemmed |
Genome-wide association study identifies the SERPINB gene cluster as a susceptibility locus for food allergy |
| title_sort |
genome-wide association study identifies the serpinb gene cluster as a susceptibility locus for food allergy |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/9babf9e0239a43b69d6b7286939ba997 |
| work_keys_str_mv |
AT ingomarenholz genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT sarahgrosche genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT birgitkalb genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT franzruschendorf genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT katharinablumchen genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT rupertschlags genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT nedaharandi genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT mareikeprice genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT gesinehansen genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT jurgenseidenberg genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT holgerroblitz genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT songulyurek genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT sebastiantschirner genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT xiumeihong genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT xiaobinwang genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT georghomuth genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT carstenoschmidt genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT markusmnothen genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT norberthubner genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT bodoniggemann genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT kirstenbeyer genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy AT youngaelee genomewideassociationstudyidentifiestheserpinbgeneclusterasasusceptibilitylocusforfoodallergy |
| _version_ |
1718390254298202112 |