One Year of SARS-CoV-2: Genomic Characterization of COVID-19 Outbreak in Qatar

Qatar, a country with a strong health system and a diverse population consisting mainly of expatriate residents, has experienced two large waves of COVID-19 outbreak. In this study, we report on 2634 SARS-CoV-2 whole-genome sequences from infected patients in Qatar between March-2020 and March-2021,...

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Autores principales:	Fatiha M. Benslimane, Hebah A. Al Khatib, Ola Al-Jamal, Dana Albatesh, Sonia Boughattas, Ayeda A Ahmed, Meryem Bensaad, Shameem Younuskunju, Yasmin A. Mohamoud, Mashael Al Badr, Abdalla A. Mohamed, Reham A. El-Kahlout, Tasneem Al-Hamad, Dina Elgakhlab, Fatima H. Al-Kuwari, Chadi Saad, Andrew Jeremijenko, Abdullatif Al-Khal, Muna A. Al-Maslamani, Roberto Bertollini, Einas A. Al-Kuwari, Hamad E. Al-Romaihi, Salih Al-Marri, Mohammed Al-Thani, Radja M. Badji, Hamdi Mbarek, Yasser Al-Sarraj, Joel A. Malek, Said I. Ismail, Laith J. Abu-Raddad, Peter V. Coyle, Asmaa A. Al Thani, Hadi M. Yassine
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	SARS-CoV-2 COVID19 variant analysis Qatar N481K Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/9bc184c8503742488eed928ed0480af6
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spelling	oai:doaj.org-article:9bc184c8503742488eed928ed0480af62021-11-18T07:37:35ZOne Year of SARS-CoV-2: Genomic Characterization of COVID-19 Outbreak in Qatar2235-298810.3389/fcimb.2021.768883https://doaj.org/article/9bc184c8503742488eed928ed0480af62021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fcimb.2021.768883/fullhttps://doaj.org/toc/2235-2988Qatar, a country with a strong health system and a diverse population consisting mainly of expatriate residents, has experienced two large waves of COVID-19 outbreak. In this study, we report on 2634 SARS-CoV-2 whole-genome sequences from infected patients in Qatar between March-2020 and March-2021, representing 1.5% of all positive cases in this period. Despite the restrictions on international travel, the viruses sampled from the populace of Qatar mirrored nearly the entire global population’s genomic diversity with nine predominant viral lineages that were sustained by local transmission chains and the emergence of mutations that are likely to have originated in Qatar. We reported an increased number of mutations and deletions in B.1.1.7 and B.1.351 lineages in a short period. These findings raise the imperative need to continue the ongoing genomic surveillance that has been an integral part of the national response to monitor the SARS-CoV-2 profile and re-emergence in Qatar.Fatiha M. BenslimaneHebah A. Al KhatibOla Al-JamalDana AlbateshSonia BoughattasAyeda A AhmedMeryem BensaadShameem YounuskunjuYasmin A. MohamoudMashael Al BadrAbdalla A. MohamedReham A. El-KahloutTasneem Al-HamadDina ElgakhlabFatima H. Al-KuwariChadi SaadAndrew JeremijenkoAbdullatif Al-KhalMuna A. Al-MaslamaniRoberto BertolliniEinas A. Al-KuwariHamad E. Al-RomaihiSalih Al-MarriMohammed Al-ThaniRadja M. BadjiHamdi MbarekYasser Al-SarrajJoel A. MalekJoel A. MalekSaid I. IsmailLaith J. Abu-RaddadLaith J. Abu-RaddadLaith J. Abu-RaddadPeter V. CoyleAsmaa A. Al ThaniHadi M. YassineHadi M. YassineFrontiers Media S.A.articleSARS-CoV-2COVID19variant analysisQatarN481KMicrobiologyQR1-502ENFrontiers in Cellular and Infection Microbiology, Vol 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	SARS-CoV-2 COVID19 variant analysis Qatar N481K Microbiology QR1-502
spellingShingle	SARS-CoV-2 COVID19 variant analysis Qatar N481K Microbiology QR1-502 Fatiha M. Benslimane Hebah A. Al Khatib Ola Al-Jamal Dana Albatesh Sonia Boughattas Ayeda A Ahmed Meryem Bensaad Shameem Younuskunju Yasmin A. Mohamoud Mashael Al Badr Abdalla A. Mohamed Reham A. El-Kahlout Tasneem Al-Hamad Dina Elgakhlab Fatima H. Al-Kuwari Chadi Saad Andrew Jeremijenko Abdullatif Al-Khal Muna A. Al-Maslamani Roberto Bertollini Einas A. Al-Kuwari Hamad E. Al-Romaihi Salih Al-Marri Mohammed Al-Thani Radja M. Badji Hamdi Mbarek Yasser Al-Sarraj Joel A. Malek Joel A. Malek Said I. Ismail Laith J. Abu-Raddad Laith J. Abu-Raddad Laith J. Abu-Raddad Peter V. Coyle Asmaa A. Al Thani Hadi M. Yassine Hadi M. Yassine One Year of SARS-CoV-2: Genomic Characterization of COVID-19 Outbreak in Qatar
description	Qatar, a country with a strong health system and a diverse population consisting mainly of expatriate residents, has experienced two large waves of COVID-19 outbreak. In this study, we report on 2634 SARS-CoV-2 whole-genome sequences from infected patients in Qatar between March-2020 and March-2021, representing 1.5% of all positive cases in this period. Despite the restrictions on international travel, the viruses sampled from the populace of Qatar mirrored nearly the entire global population’s genomic diversity with nine predominant viral lineages that were sustained by local transmission chains and the emergence of mutations that are likely to have originated in Qatar. We reported an increased number of mutations and deletions in B.1.1.7 and B.1.351 lineages in a short period. These findings raise the imperative need to continue the ongoing genomic surveillance that has been an integral part of the national response to monitor the SARS-CoV-2 profile and re-emergence in Qatar.
format	article
author	Fatiha M. Benslimane Hebah A. Al Khatib Ola Al-Jamal Dana Albatesh Sonia Boughattas Ayeda A Ahmed Meryem Bensaad Shameem Younuskunju Yasmin A. Mohamoud Mashael Al Badr Abdalla A. Mohamed Reham A. El-Kahlout Tasneem Al-Hamad Dina Elgakhlab Fatima H. Al-Kuwari Chadi Saad Andrew Jeremijenko Abdullatif Al-Khal Muna A. Al-Maslamani Roberto Bertollini Einas A. Al-Kuwari Hamad E. Al-Romaihi Salih Al-Marri Mohammed Al-Thani Radja M. Badji Hamdi Mbarek Yasser Al-Sarraj Joel A. Malek Joel A. Malek Said I. Ismail Laith J. Abu-Raddad Laith J. Abu-Raddad Laith J. Abu-Raddad Peter V. Coyle Asmaa A. Al Thani Hadi M. Yassine Hadi M. Yassine
author_facet	Fatiha M. Benslimane Hebah A. Al Khatib Ola Al-Jamal Dana Albatesh Sonia Boughattas Ayeda A Ahmed Meryem Bensaad Shameem Younuskunju Yasmin A. Mohamoud Mashael Al Badr Abdalla A. Mohamed Reham A. El-Kahlout Tasneem Al-Hamad Dina Elgakhlab Fatima H. Al-Kuwari Chadi Saad Andrew Jeremijenko Abdullatif Al-Khal Muna A. Al-Maslamani Roberto Bertollini Einas A. Al-Kuwari Hamad E. Al-Romaihi Salih Al-Marri Mohammed Al-Thani Radja M. Badji Hamdi Mbarek Yasser Al-Sarraj Joel A. Malek Joel A. Malek Said I. Ismail Laith J. Abu-Raddad Laith J. Abu-Raddad Laith J. Abu-Raddad Peter V. Coyle Asmaa A. Al Thani Hadi M. Yassine Hadi M. Yassine
author_sort	Fatiha M. Benslimane
title	One Year of SARS-CoV-2: Genomic Characterization of COVID-19 Outbreak in Qatar
title_short	One Year of SARS-CoV-2: Genomic Characterization of COVID-19 Outbreak in Qatar
title_full	One Year of SARS-CoV-2: Genomic Characterization of COVID-19 Outbreak in Qatar
title_fullStr	One Year of SARS-CoV-2: Genomic Characterization of COVID-19 Outbreak in Qatar
title_full_unstemmed	One Year of SARS-CoV-2: Genomic Characterization of COVID-19 Outbreak in Qatar
title_sort	one year of sars-cov-2: genomic characterization of covid-19 outbreak in qatar
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/9bc184c8503742488eed928ed0480af6
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One Year of SARS-CoV-2: Genomic Characterization of COVID-19 Outbreak in Qatar

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