Pre- and postmortem imaging of transplanted cells

Anna Andrzejewska,1 Adam Nowakowski,1 Miroslaw Janowski,1–4 Jeff WM Bulte,3–7 Assaf A Gilad,3,4 Piotr Walczak,3,4,8 Barbara Lukomska11NeuroRepair Department, 2Department of Neurosurgery, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland; 3Russell H M...

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Autores principales:	Andrzejewska A, Nowakowski A, Janowski M, Bulte JWM, Gilad AA, Walczak P, Lukomska B
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/9bc2c8e1e137497b91d048ab017ae296
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spelling	oai:doaj.org-article:9bc2c8e1e137497b91d048ab017ae2962021-12-02T03:11:42ZPre- and postmortem imaging of transplanted cells1178-2013https://doaj.org/article/9bc2c8e1e137497b91d048ab017ae2962015-09-01T00:00:00Zhttp://www.dovepress.com/pre--and-postmortem-imaging-of-transplanted-cells-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013Anna Andrzejewska,1 Adam Nowakowski,1 Miroslaw Janowski,1–4 Jeff WM Bulte,3–7 Assaf A Gilad,3,4 Piotr Walczak,3,4,8 Barbara Lukomska11NeuroRepair Department, 2Department of Neurosurgery, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland; 3Russell H Morgan Department of Radiology and Radiological Science, Division of MR Research, 4Cellular Imaging Section and Vascular Biology Program, Institute for Cell Engineering, 5Department of Biomedical Engineering, 6Department of Chemical & Biomolecular Engineering, 7Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; 8Department of Radiology, Faculty of Medical Sciences, University of Warmia and Mazury, Olsztyn, PolandAbstract: Therapeutic interventions based on the transplantation of stem and progenitor cells have garnered increasing interest. This interest is fueled by successful preclinical studies for indications in many diseases, including the cardiovascular, central nervous, and musculoskeletal system. Further progress in this field is contingent upon access to techniques that facilitate an unambiguous identification and characterization of grafted cells. Such methods are invaluable for optimization of cell delivery, improvement of cell survival, and assessment of the functional integration of grafted cells. Following is a focused overview of the currently available cell detection and tracking methodologies that covers the entire spectrum from pre- to postmortem cell identification.Keywords: stem cells, transplantation, SPECT, MRI, bioluminescence, cell labelingAndrzejewska ANowakowski AJanowski MBulte JWMGilad AAWalczak PLukomska BDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2015, Iss default, Pp 5543-5559 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Andrzejewska A Nowakowski A Janowski M Bulte JWM Gilad AA Walczak P Lukomska B Pre- and postmortem imaging of transplanted cells
description	Anna Andrzejewska,1 Adam Nowakowski,1 Miroslaw Janowski,1–4 Jeff WM Bulte,3–7 Assaf A Gilad,3,4 Piotr Walczak,3,4,8 Barbara Lukomska11NeuroRepair Department, 2Department of Neurosurgery, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland; 3Russell H Morgan Department of Radiology and Radiological Science, Division of MR Research, 4Cellular Imaging Section and Vascular Biology Program, Institute for Cell Engineering, 5Department of Biomedical Engineering, 6Department of Chemical & Biomolecular Engineering, 7Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; 8Department of Radiology, Faculty of Medical Sciences, University of Warmia and Mazury, Olsztyn, PolandAbstract: Therapeutic interventions based on the transplantation of stem and progenitor cells have garnered increasing interest. This interest is fueled by successful preclinical studies for indications in many diseases, including the cardiovascular, central nervous, and musculoskeletal system. Further progress in this field is contingent upon access to techniques that facilitate an unambiguous identification and characterization of grafted cells. Such methods are invaluable for optimization of cell delivery, improvement of cell survival, and assessment of the functional integration of grafted cells. Following is a focused overview of the currently available cell detection and tracking methodologies that covers the entire spectrum from pre- to postmortem cell identification.Keywords: stem cells, transplantation, SPECT, MRI, bioluminescence, cell labeling
format	article
author	Andrzejewska A Nowakowski A Janowski M Bulte JWM Gilad AA Walczak P Lukomska B
author_facet	Andrzejewska A Nowakowski A Janowski M Bulte JWM Gilad AA Walczak P Lukomska B
author_sort	Andrzejewska A
title	Pre- and postmortem imaging of transplanted cells
title_short	Pre- and postmortem imaging of transplanted cells
title_full	Pre- and postmortem imaging of transplanted cells
title_fullStr	Pre- and postmortem imaging of transplanted cells
title_full_unstemmed	Pre- and postmortem imaging of transplanted cells
title_sort	pre- and postmortem imaging of transplanted cells
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/9bc2c8e1e137497b91d048ab017ae296
work_keys_str_mv	AT andrzejewskaa preandpostmortemimagingoftransplantedcells AT nowakowskia preandpostmortemimagingoftransplantedcells AT janowskim preandpostmortemimagingoftransplantedcells AT bultejwm preandpostmortemimagingoftransplantedcells AT giladaa preandpostmortemimagingoftransplantedcells AT walczakp preandpostmortemimagingoftransplantedcells AT lukomskab preandpostmortemimagingoftransplantedcells
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Pre- and postmortem imaging of transplanted cells

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